The Effect of Patient Position Changes on Advanced Cardiac Indices in Cancer Surgery

Completed

• Conditions: Cardiac Indices; Abdominal Cancer; Blood Pressure
• Interventions: Procedure: cardiac indices in supine and trendelenburg position

• Registration Number: NCT06293391
• Lead Sponsor: Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital

Brief Summary

Esophageal Doppler Monitoring (Deltex CardioQ Esophageal Doppler Monitor, ODM) is used to manage patients' fluid therapy by non-invasively measuring continuous cardiac output with an esophageal probe. The aim of this study was to compare the effects of patient position changes on cardiac indices and vital signs in patients who underwent major abdominal cancer surgery with laparoscopic and open surgery using ODM.

Detailed Description

Patients who underwent major abdominal cancer surgery using ODM in the operating room of our hospital between November 2021 and November 2022 were identified from the Anesthesiology Clinic records and examined according to whether they were operated with open or closed (laparoscopic) methods. Demographic data, vital signs, amount of bleeding, type and amount of fluid administered, and the results of cardiac index measurements performed with the ODM device in the supine and trendelenburg positions (45 degrees) were analyzed. Parameters recorded with the ODM device; CO: Cardiac output, FTc: Flow time corrected, PV: Peak velocity, SD: Stroke distance.

Study Timeline

• Study Start: 2023-02-01
• Primary Completion: 2023-03-01
• Study Completion: 2024-02-05
• Study First Submitted: 2024-02-15
• Study First Submitted QC: 2024-02-27
• Study First Posted: 2024-03-05
• Status Verified: 2024-11
• Last Update Submitted: 2024-11-06
• Last Update Posted: 2024-11-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• Elective operation
• ASA 1-4

Exclusion Criteria

• Heart failure
• Valvular heart disease,
• Patients with symptomatic rhythm disturbances
• ODM placement contraindicated (coagulopathy, oesophageal varices, known aortic aneurysm)

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
ODM measurements of patients undergoing laparoscopic surgery in supine and trendelenburg position	cardiac indices in supine and trendelenburg position	After intubation, serial ODM measurements were performed in the supine and trendelenburg position of the patient and CO: Cardiac output, FTc: Flow time corrected, PV: Peak velocity, SD: Stroke distance values were recorded.
ODM measurements of patients undergoing open surgery in supine and trendelenburg position	cardiac indices in supine and trendelenburg position	After intubation, serial ODM measurements were performed in the supine and trendelenburg position of the patient and CO: Cardiac output, FTc: Flow time corrected, PV: Peak velocity, SD: Stroke distance values were recorded.

Primary Outcome Measures

Name	Time	Method
Stroke Volume	Immediately after induction of anaesthesia and at any stable time during the case	Measurement of cardiac output with the oesophageal doppler device immediately after induction of anaesthesia and in the middle of the case in both supine and trendelenburg position of the patient to see whether there is a significant difference in positional change.
Cardiac Output	Immediately after induction of anaesthesia and at any stable time during the case	Measurement of cardiac output with the oesophageal doppler device immediately after induction of anaesthesia and in the middle of the case in both supine and trendelenburg position of the patient to see whether there is a significant difference in positional change.
Stroke Distance	Immediately after induction of anaesthesia and at any stable time during the case	Measurement of cardiac output with the oesophageal doppler device immediately after induction of anaesthesia and in the middle of the case in both supine and trendelenburg position of the patient to see whether there is a significant difference in positional change.
Flow time corrected	Immediately after induction of anaesthesia and at any stable time during the case	Measurement of cardiac output with the oesophageal doppler device immediately after induction of anaesthesia and in the middle of the case in both supine and trendelenburg position of the patient to see whether there is a significant difference in positional change.
Pulse	Immediately after induction of anaesthesia and at any stable time during the case	Measurement of cardiac output with the oesophageal doppler device immediately after induction of anaesthesia and in the middle of the case in both supine and trendelenburg position of the patient to see whether there is a significant difference in positional change.
Peak Velocity	Immediately after induction of anaesthesia and at any stable time during the case	Measurement of cardiac output with the oesophageal doppler device immediately after induction of anaesthesia and in the middle of the case in both supine and trendelenburg position of the patient to see whether there is a significant difference in positional change.
Mean arterial pressure	Immediately after induction of anaesthesia and at any stable time during the case	Measurement of cardiac output with the oesophageal doppler device immediately after induction of anaesthesia and in the middle of the case in both supine and trendelenburg position of the patient to see whether there is a significant difference in positional change.

Trial Locations

Locations (1)

Dr.Abdurrahman Yurtaslan Ankara Oncology Train and Research Hospital; 🇹🇷 Ankara, Turkey