Clinical Features and Results of Children Receiving Respiratory Support in Pediatric Intensive Care Unit

Completed

Conditions: Respiratory disorders in diseasesclassified elsewhere,

Registration Number: CTRI/2023/05/053144

Lead Sponsor: Kulal Prasali Sadashiva

Brief Summary: Most of the children in the Pediatric Intensive Care Unit (PICU) require respiratory support. This prospective observational study will investigate the trends in clinical characteristics and outcomes of children on respiratory support in the Pediatric Intensive Care Unit. Analyzing the trends in clinical characteristics will help in identifying the

etiologies that require respiratory support the most. Additionally, this study will help to explore the common reasons for initiating and escalating respiratory support in children. Furthermore, the outcomes of this study will find relation between PIM3 score and other factors that may lead to mortality and need for invasive ventilation. The primary outcomes include 1) Clinical characteristics of individuals on respiratory support in PICU. 2) Indication for respiratory support. 3) Average days on respiratory support. 4) Average length of stay in PICU in days. 5) Mortality Rate in percentage. The secondary outcomes include 1) Most frequently used mode of Invasive ventilation. 2) Factors associated with the outcome of patients on respiratory support. 3) Indication for escalation of respiratory support. The ancillary outcomes include: 1) Association between characteristics of children on respiratory support and mortality. 2) Association between characteristics on respiratory support and type of respiratory support. 3) Association between age and primary diagnosis of children on respiratory support. 4) Correlation between various factors.

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: All

Target Recruitment: 120

Inclusion Criteria

Pediatrics less than equal to 18 years on respiratory support in Pediatric Intensive Care Unit.

Exclusion Criteria

Infants with < 2 months of age.

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1) Clinical characteristics of individuals on respiratory support in PICU.	1) Within 48 hours of admission to PICU. \| 2) Immediately when respiratory support is initiated. \| 3) Noted from initiation to termination of respiratory support. \| 4) Noted from admission to discharge/death. \| 5) After declaration of death.
4) Average length of stay in PICU in days.	1) Within 48 hours of admission to PICU. \| 2) Immediately when respiratory support is initiated. \| 3) Noted from initiation to termination of respiratory support. \| 4) Noted from admission to discharge/death. \| 5) After declaration of death.
2) Indication for respiratory support.	1) Within 48 hours of admission to PICU. \| 2) Immediately when respiratory support is initiated. \| 3) Noted from initiation to termination of respiratory support. \| 4) Noted from admission to discharge/death. \| 5) After declaration of death.
3) Average days on respiratory support.	1) Within 48 hours of admission to PICU. \| 2) Immediately when respiratory support is initiated. \| 3) Noted from initiation to termination of respiratory support. \| 4) Noted from admission to discharge/death. \| 5) After declaration of death.
5) Mortality Rate in percentage.	1) Within 48 hours of admission to PICU. \| 2) Immediately when respiratory support is initiated. \| 3) Noted from initiation to termination of respiratory support. \| 4) Noted from admission to discharge/death. \| 5) After declaration of death.

Secondary Outcome Measures

Name	Time	Method
1) Most frequently used mode of Invasive ventilation.	2) Factors associated with outcome of patients on respiratory support.

Trial Locations

Locations (1): Kasturba Hospital
🇮🇳
Udupi, KARNATAKA, India
Kasturba Hospital
🇮🇳Udupi, KARNATAKA, India
Kulal Prasali Sadashiva
Principal investigator
8692958775
prasali.mchpmpl2022@learner.manipal.edu