Investigation of the validity and improvement of the utility of claims data for quality improvement of treatment of sepsis in hospitals

• Conditions: B37.7; B49; O75.3; O85; P36; R65.0; R65.1; R57.2; Salmonella sepsis; Bubonic plague

• Registration Number: DRKS00017775
• Lead Sponsor: niversitätsklinikum Jena

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-10-14
• Study Completion: 2021-10-14
• Results First Posted: 2023-09-09
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 10384

Inclusion Criteria

Billing based on DRG, inpatient cases, age of at least 15 years, discharge from hospital in years 2015-2017

Exclusion Criteria

none

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Estimation of the validity (sensitivity, specificity, positive and negative predicitve value) of ICD-coding of sepsis with organ dysfunction including septic shock in German hospital claims data.

Secondary Outcome Measures

Name	Time	Method
a) Proportion of sepsis (without organ dysfunction, with organ dysfunction, septic shock) based on old sepsis-definitions (sepsis-1)<br>b) Proportion of sepsis (sepsis, septic shock) based on new sepsis-definitions (sepsis-3)<br>c) Validity (sensitivity, specificity, positive and negative predictive value) of different methods to identify sepsis based on ICD-codes and German procedure (OPS) codes<br>d) Validity (sensitivity, specificity, positive and negative predictive value) mortality risk-factors identified in claims data