The Therapeutic Efficacy of Neurofeedback in Depression
- Conditions
- Depression
- Registration Number
- NCT00729547
- Lead Sponsor
- Korea University
- Brief Summary
The investigators examined the therapeutic efficacy of neurofeedback in depression subjects. The investigators hypothesize that 5 weeks neurofeedback training will be able to alleviate depressive symptoms.
- Detailed Description
Subject
* Fulfilled DSM-IV criteria for depressive disorders.
* Persons who had organic disorders were excluded.
* Who had been treated by psychoactive drugs for at least 2 months prior to the study were excluded.
Design
* Subjects were randomly assigned to two groups (EEG biofeedback /psychotherapy placebo) by block randomization.
* EEG biofeedback training was provided for 5 weeks(10 sessions, twice per week). Each training session was composed of 6 four minute trials followed by 5 thirty second rest periods
* Psychotherapy placebo session was provided for 5 weeks. These sessions consisted of additional assessment, interpretation of the test results and providing information on course and treatment of mood disorder.
* After subjects completed the training, they participated in a month-long (twice per week) self-training session to maintain a similar mental state during neurofeedback training sessions without feedback system's assistance.
* Subjects who had finished the psychotherapy placebo were referred to other therapists as necessary.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 24
- clinical diagnosis of mood disorder
- right handed
- current BDI-2 score exceed 10
- with psychotic symptom
- with organic disorders
- treated by psychoactive drugs for at least 2 months prior to the study
- history of pathologic alcohol use
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- FACTORIAL
- Primary Outcome Measures
Name Time Method frontal EEG asymmetry indexes 5 weeks
- Secondary Outcome Measures
Name Time Method BDI-2 5 weeks
Trial Locations
- Locations (1)
Department of Oriental Neuropsychiatry, Kyunghee Medical Center
🇰🇷Seoul, Korea, Republic of
Department of Oriental Neuropsychiatry, Kyunghee Medical Center🇰🇷Seoul, Korea, Republic of