NCT00729547已完成不适用
The Therapeutic Efficacy of Frontal EEG Asymmetry Neurofeedback in Depression
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 24
- 试验地点
- 2
- 主要终点
- frontal EEG asymmetry indexes
研究概览
简要总结
The investigators examined the therapeutic efficacy of neurofeedback in depression subjects. The investigators hypothesize that 5 weeks neurofeedback training will be able to alleviate depressive symptoms.
详细描述
Subject
- Fulfilled DSM-IV criteria for depressive disorders.
- Persons who had organic disorders were excluded.
- Who had been treated by psychoactive drugs for at least 2 months prior to the study were excluded.
Design
- Subjects were randomly assigned to two groups (EEG biofeedback /psychotherapy placebo) by block randomization.
- EEG biofeedback training was provided for 5 weeks(10 sessions, twice per week). Each training session was composed of 6 four minute trials followed by 5 thirty second rest periods
- Psychotherapy placebo session was provided for 5 weeks. These sessions consisted of additional assessment, interpretation of the test results and providing information on course and treatment of mood disorder.
- After subjects completed the training, they participated in a month-long (twice per week) self-training session to maintain a similar mental state during neurofeedback training sessions without feedback system's assistance.
- Subjects who had finished the psychotherapy placebo were referred to other therapists as necessary.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Factorial
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 60 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •clinical diagnosis of mood disorder
- •right handed
- •current BDI-2 score exceed 10
排除标准
- •with psychotic symptom
- •with organic disorders
- •treated by psychoactive drugs for at least 2 months prior to the study
- •history of pathologic alcohol use
结局指标
主要结局
frontal EEG asymmetry indexes
时间窗: 5 weeks
次要结局
- BDI-2(5 weeks)
研究者
研究点 (2)
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