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临床试验/NCT00729547
NCT00729547已完成不适用

The Therapeutic Efficacy of Frontal EEG Asymmetry Neurofeedback in Depression

Korea University2 个研究点 分布在 1 个国家目标入组 24 人开始时间: 2006年9月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
24
试验地点
2
主要终点
frontal EEG asymmetry indexes

研究概览

简要总结

The investigators examined the therapeutic efficacy of neurofeedback in depression subjects. The investigators hypothesize that 5 weeks neurofeedback training will be able to alleviate depressive symptoms.

详细描述

Subject

  • Fulfilled DSM-IV criteria for depressive disorders.
  • Persons who had organic disorders were excluded.
  • Who had been treated by psychoactive drugs for at least 2 months prior to the study were excluded.

Design

  • Subjects were randomly assigned to two groups (EEG biofeedback /psychotherapy placebo) by block randomization.
  • EEG biofeedback training was provided for 5 weeks(10 sessions, twice per week). Each training session was composed of 6 four minute trials followed by 5 thirty second rest periods
  • Psychotherapy placebo session was provided for 5 weeks. These sessions consisted of additional assessment, interpretation of the test results and providing information on course and treatment of mood disorder.
  • After subjects completed the training, they participated in a month-long (twice per week) self-training session to maintain a similar mental state during neurofeedback training sessions without feedback system's assistance.
  • Subjects who had finished the psychotherapy placebo were referred to other therapists as necessary.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Factorial
主要目的
Treatment
盲法
None

入排标准

年龄范围
20 Years 至 60 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • clinical diagnosis of mood disorder
  • right handed
  • current BDI-2 score exceed 10

排除标准

  • with psychotic symptom
  • with organic disorders
  • treated by psychoactive drugs for at least 2 months prior to the study
  • history of pathologic alcohol use

结局指标

主要结局

frontal EEG asymmetry indexes

时间窗: 5 weeks

次要结局

  • BDI-2(5 weeks)

研究者

申办方类型
Other

研究点 (2)

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