Social anxiety and stress reactivity in Autism Spectrum Disorders

Completed

• Conditions: autism; autism spectrum disorders; 10012562

• Registration Number: NL-OMON43805
• Lead Sponsor: GGZ Eindhoven (Eindhoven)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2018-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 101

Inclusion Criteria

- Age between 18 and 65 years.
- Presence of ASD diagnosis according to DSM-5 criteria, and as assessed with the ADOS-2 module 4 revised: Total score * 8 (section Social Affect and section Restricted and Repetitive Behavior; with section social affect * 6)
- Intelligence: Verbal Comprehension (VCI), Perceptual Reasoning (PRI) is * 70
- Minimal (max. 2 years) psychological and/ or psychiatric treatment history.;Control group:
- Age between 18 and 65 years
- Not diagnosed with ASD or any other lifetime psychiatric diagnosis
- No first-degree relative with ASD
- AQ < 26
- Intelligence: Verbal Comprehension (VCI), Perceptual Reasoning (PRI) is * 70

Exclusion Criteria

- Specific somatic disorders: known genetic abnormality, metabolic disorder, epilepsy, traumatic brain injury
- Suicidal tendencies, acute psychosis, bipolar disorder
- Clinical treatment (admission) history for any psychiatric disorder

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The levels of social anxiety, psychological and biological stress reactivity,<br /><br>cortisollevels.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Comorbid subclinical psychotic reactivity in response to stress.</p><br>