The effectiveness of harpagophytum procumbens cream in the relief of osteoarthritic pain of the knee
Completed
- Conditions
- Osteoarthritis of the kneeMusculoskeletal Diseases
- Registration Number
- ISRCTN13351989
- Lead Sponsor
- Synapse Hellenic Pharmaceuticals & Services
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 400
Inclusion Criteria
1. Osteoarthritis Stage (Kellgren & Lawrence Scale) 2 - 3
2. Patient’s Knee - Pain Self Evaluation (VAS 0 - 10) 4, 5, 6, 7
Exclusion Criteria
1. Osteoarthritis Stage (Kellgren & Lawrence Scale) 0, 1, 4
2. Patient’s Knee- Pain Self Evaluation (VAS 0 - 10) 0 – 3 , 8 - 10
3. Use of analgesic or anti-inflammatory medications, topical or oral on the day of the study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Patient improvement on pain as evaluated by a Visual Analogue Scale (0-10) ten minutes after application of the cream.<br>
- Secondary Outcome Measures
Name Time Method
Related Research Topics
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What are the molecular mechanisms by which Harpagophytum procumbens cream alleviates knee osteoarthritis pain?
How does Harpagophytum procumbens cream compare to NSAIDs in managing knee osteoarthritis pain severity and duration?
Are there specific biomarkers that correlate with improved outcomes in knee osteoarthritis patients using Harpagophytum procumbens cream?
What adverse events have been reported with topical Harpagophytum procumbens formulations in musculoskeletal pain trials?
What are the potential synergistic effects of combining Harpagophytum procumbens cream with hyaluronic acid injections for knee osteoarthritis?