NCT02682394Unknown不适用
Prognostic Importance of Quantitative Magnetic Resonance Imaging for Evaluation of Pancreatic Steatosis in Patients With Pancreatic Cancer
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Percentage of fat in pancreas measured in the head, body and tail excluding the lesion area.
研究概览
简要总结
Prognostic Importance of Quantitative Magnetic Resonance Imaging for Evaluation of Pancreatic Steatosis in Patients with Pancreatic Cancer
详细描述
- Finding patients with pancreatic cancer (in all stages), before any treatment.
- Non invasively quantify fatty infiltration of pancreas using, MRI DIXON Scan in pancreatic cancer patient relatively to liver.
- Measuring cell-free blood DNA in those patients for evaluating the aggressiveness of the disease.
- Quantify the prognostic significance of pancreatic steatosis in comparison with clinical and pathological prognostic indexes used today.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients diagnosed with any pancreatic cancer, in any stage, before treatment.
排除标准
- •claustrophobia
- •patients with non mri compatible devices (e.g. orthopaedic external fixation system)
- •After chemotherapy treatment or surgical procedure
结局指标
主要结局
Percentage of fat in pancreas measured in the head, body and tail excluding the lesion area.
时间窗: at 24 hours before chemotherapy starting
measuring Pancreatic Steatosis in patients with pancreatic cancer using MRI DIXON scan, at 24 hours before chemotherapy starting.
Blood levels of free DNA
时间窗: The blood sample taken 15 minutes prior to MRI study, at time of IV access.
Correlation of free DNA level and metastatic spread.
次要结局
未报告次要终点
研究者
研究点 (1)
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