Measles Vaccine: Is There a Protective Role in COVID 19 Pandemic?
试验速览
- 阶段
- 不适用
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Viral clearance
研究概览
简要总结
The following two mechanisms that explain the ability of measles vaccine to cause partial protection against COVID-19. The first is that measles vaccine may increase the ability of the immune system to fight off pathogens other than measles due to the generated bystander immunity that would enhance the overall immunity against the new coronavirus. The second is that SARS-CoV-2 is proven to have structure similarities with measles, which may cause cross-reactivity and immunity between measles vaccines and COVID-19, leading to partial protection against COVID-19 in vaccinated subjects
详细描述
Objectives:
- To identify Measles IgG titre in SARS-COV2 infected patients .
- correlate level of Measles IgG titre with the clinical severity of COVID-19 disease.
Secondary Objective To find an association of the postulated protective role of measles vaccine and SARS-COV2 infection
Criteria:
Inclusion criteria:included patients would be divided into 3 groups according to clinical severity of COVID-19 disease (mild ,moderate & severe)
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients with confirmed COVID
- •Any age or gender
排除标准
- •- Any patient refusing to be involved in the study
结局指标
主要结局
Viral clearance
时间窗: 6 months
Achievement of two consecutive negative PCR results for COVID 19 and discharge from hospital
次要结局
未报告次要终点
研究者
Amira Al Balakosy
Tropical Medicine Department. Ain Shams University
Ain Shams University