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临床试验/NCT05392777
NCT05392777已完成不适用

Utility of Residual Syntax Score to Predict Outcome After Acute Myocardial Infarction

Cairo University1 个研究点 分布在 1 个国家目标入组 490 人开始时间: 2021年11月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
490
试验地点
1
主要终点
Composite of major adverse cardiovascular events (MACE).

研究概览

简要总结

The aim of this study is to evaluate the utility of residual syntax score after PCI of the culprit vessel for patients with AMI (STEMI or NSTEMI) to predict 6-months clinical outcomes.

详细描述

A- Study Design: Prospective cross-sectional analytic study

B- Study Protocol: After attaining written informed consents from eligible STEMI/NSTEMI patients for participation in this observational study, data collection will be as follows: -

  1. Targeted history taking emphasizing on:
  • Age of the patient, gender, and other risk-factors as hypertension, diabetes mellitus, smoking, substance abuse, dyslipidemia or family history of premature CAD.
  • Symptoms as chest pain and time of onset, previous CAD related symptoms, therapies or revascularization procedures.
  • Any relevant comorbid conditions.
  • Time delays labelled as patient related delay, door-to-first medical contact, any delays of transfer, door-to-needle or -to-wire crossing will be recorded.
  1. Examination:

Targeted physical examination of the patients with special emphasis on heart rate, blood pressure at presentation, Killip class (I-to-IV), signs suggestive of mechanical complications (new murmurs, pulmonary edema or cardiogenic shock).

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
18 Years 至 85 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Acute myocardial infarction (STEMI or NSTEMI)

排除标准

  • Refusal to participate in the study.
  • In case of NSTEMI, patients with unrecognizable culprit lesion will be excluded.
  • Patients with previous coronary bypass surgery.

结局指标

主要结局

Composite of major adverse cardiovascular events (MACE).

时间窗: 6 months

Composite of MACE (defined as; CV death, non-fatal MI, non-fatal stroke)

次要结局

  • Rates of cerebrovascular stroke(6 months)
  • Rates of heart failure manifestations(6 months)
  • Rates of ischaemia-deriven unplanned revascularization(6 months)
  • Rates of myocardial infarction(6 months)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Ahmad Samir

Principal investigator - Consultant

Cairo University

研究点 (1)

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