Effect of dexamethasone combined with VB12 on early postoperative outcomes in percutaneous endoscopic interlaminar discectomy:a randomized control study
- Conditions
- lumbar disc herniation
- Registration Number
- ChiCTR2400088854
- Lead Sponsor
- The 908th Hospital of Chinese People’s Liberation Army Joint Logistic Support Force
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
(1) diagnosis of lumbar intervertebral disc herniation, ineffective after strict conservative treatment for more than 3 months; (2) patients' symptoms, signs and imaging manifestations were compatible, and the responsible interspace was L4/5 or L5/S1 level; (3) there were no obvious contraindications to surgery in the preoperative examination.
(1) multiple segmental lesions all requiring surgery or recurrence after surgical treatment; (2) combined cardiopulmonary, hepatic, and renal functions with severe impairment; (3) complicated intervertebral space infections or postoperative wound infections; (4) hypersensitivity to dexamethasone and vitamin B12, or contraindications to their use; (5) incomplete clinical data, inability to cooperate with the follow-up visit, and refusal to sign the informed consent form.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The Visual Analog Scale scores;
- Secondary Outcome Measures
Name Time Method 0swestry disability index;Japanese Orthopaedic Association Scores;Modified MacNab efficacy evaluation criteria;PGE2;TNF-a;IL-6;