Effects of Inspiratory Muscle Training in Patients With Sarcoidosis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 主要终点
- Maximum inspiratory and expiratory muscle strength (MIP, MEP)
研究概览
简要总结
Respiratory muscle weakness results with decreased exercise capacity, worse fatigue, dyspnea and quality of life in patients with sarcoidosis. However, no study investigated the effects of inspiratory muscle training (IMT), therefore effects of IMT on outcomes in patients with sarcoidosis were investigated.
详细描述
Patients were diagnosed with sarcoidosis according to the criteria of the latest American Thoracic Society (ATS)/European Respiratory Society (ERS)/World Association of Sarcoidosis and Other Granulomatous (WASOG) Disorders statement on sarcoidosis. Primary outcome measurement was respiratory muscle strength, secondary outcomes were, exercise capacity quality of life, fatigue and depression.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Clinically stable
- •Under standard medication
- •Stage I and IV
- •No change in medications over three months
排除标准
- •Cognitive disorders
- •Current corticosteroid use
- •Having co-morbidity to prevent performing IMT
- •Acute infection
- •Orthopedic and neurological problems
研究组 & 干预措施
Treatment group
Intervention: Treatment group received inspiratory muscle training (IMT) using POWERbreathe Classic threshold loading device .
干预措施: Inspiratory muscle training (Device)
Control group
Sham: Control group received sham inspiratory muscle training using POWERbreathe Classic threshold loading device .
干预措施: Sham inspiratory muscle training (Device)
结局指标
主要结局
Maximum inspiratory and expiratory muscle strength (MIP, MEP)
时间窗: 6 weeks
Mouth pressure device
次要结局
- Exercise Capacity(6 weeks)
- Pulmonary function and diffusing capacity(6 weeks)
- Peripheral muscle strength(6 weeks)
- Quality of life(6 weeks)
- Depression(6 weeks)
- Fatigue(6 weeks)
- Dyspnea(6 weeks)
- Maximal Exercise Capacity(6 weeks)
研究者
Meral Boşnak Güçlü
Assoc. Prof.
Gazi University