Evaluation of the presence and the prognostic role of endogenous autoantibodies and circulating mediators in the blood of patients with sepsis and septic shock defined on the basis of the recently published new criteria.

Not Applicable

Completed

• Conditions: Sepsis; Infection - Studies of infection and infectious agents; Inflammatory and Immune System - Autoimmune diseases

• Registration Number: ACTRN12617000429358
• Lead Sponsor: niversity of Piemonte Oreintale Amedeo Avogadro

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2017-03-24
• Study Completion: 2018-07-10
• Last Update Posted: 10 December 2019

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 118

Inclusion Criteria

Inclusion criteria will be: suspected infection with at least two of the elements of the quick Sequential Organ Failure Assessment score (qSOFA)i.e., respiratory rate equal or more than 22/min, altered mental state with GCS less than 15, systolic arterial blood pressure equal or less than 100 mmHg. A written informed consent and age equal or more than 18 years and less than 85 years old will be mandatory as well. Healthy volunteers will be included if with an age equal or more than 18 years and less than 85 years old.

Exclusion Criteria

Age equal or more than 18 years; age less than 85; lack of informed consent.

Study & Design

• Study Type: Observational
• Study Design: Not specified