Physical Activity, Psychopathology, and Quality of Life in People With Psychotic or Affective Disorders

Recruiting

• Conditions: Affective Disorder; Psychotic Disorders
• Interventions: Behavioral: Physical activity and sedentary behavior education

• Registration Number: NCT05869409
• Lead Sponsor: University of Social Sciences and Humanities, Warsaw

Brief Summary

This longitudinal observational study tests the associations between physical activity, health-related quality of life, and psychopathology symptoms among people diagnosed with schizophrenia or diagnosed with affective disorders. It was assumed that higher levels of physical activity at baseline will be related to better quality of life (across physical, social, and psychological domains), and lower psychopathology symptoms (positive and negative symptoms of psychosis, general psychopathology, and depression severity) at 6-week follow-up measurement. Adult participants with a diagnosis of a psychotic disorder or a diagnosis of an affective disorder will be enrolled.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-05-01
• Status Verified: 2023-05
• Study First Submitted: 2023-05-09
• Study First Submitted QC: 2023-05-18
• Last Update Submitted: 2023-05-18
• Study First Posted: 2023-05-22
• Last Update Posted: 2023-05-22
• Primary Completion: 2025-05-01
• Study Completion: 2025-12-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• a diagnosis of a psychotic disorder or affective disorder

Exclusion Criteria

• major cognitive deficits, indicated by total scores > 8 points, obtained with the Montreal Cognitive Assessment (MoCA) Scale at baseline

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
People diagnosed with a psychotic disorder or an affective disorder	Physical activity and sedentary behavior education	-

Primary Outcome Measures

Name	Time	Method
Health-Related Quality of Life	change from the baseline health-related quality of life at 6 weeks	scores (range 0-100) obtained in the World Health Organization Quality of Life Questionnaire (WHOQOL-BREF); higher scores indicate better quality of life

Secondary Outcome Measures

Name	Time	Method
Positive Symptoms (Psychosis)	change from the baseline positive symptoms at 6 weeks	scores obtained with Positive and Negative Syndrome Scales (PANSS): Positive Symptoms subscale, scores range: 7-49; higher scores indicate more symptoms
Depression symptoms	change from baseline depression symptoms at 6 weeks	scores obtained in Patient Health Questionnaire -9 (PHQ-9); scores range: 0-36; higher scores indicate more severe symptoms of depression
General Psychopathology Symptoms )Psychosis)	change from the baseline general psychopathology symptoms at 6 weeks	scores obtained with Positive and Negative Syndrome Scales (PANSS): General Psychopathology subscale, scores range: 16-112, higher symptoms indicate more symptoms
Negative Symptoms (Psychosis)	change from the baseline negative symptoms at 6 weeks	scores obtained with Positive and Negative Syndrome Scales (PANSS): Negative Symptoms subcale, scores range: 7-49, higher scores indicate more symptoms
Physical activity	change from baseline physical activity at 6 weeks	minutes of physical activity per week measured with International Physical Activity Questionnaire - Short Form (IPAQ-Short Form); more minutes indicate more time spent on light, moderate, or high-intensity physical activity

Trial Locations

Locations (1)

SWPS University, Faculty of Psychology in Wroclaw; 🇵🇱 Wroclaw, Lower Silezia, Poland