NCT04583800招募中不适用
Prediction of Heart Failure and Cognitive Decline in Type 2 Diabetes : Longitudinal Cohort Study of Immuno-inflammation, Cardiac Energetics and Cognition.PreciDIAB-HEART&BRAIN
University Hospital, Lille1 个研究点 分布在 1 个国家目标入组 600 人开始时间: 2021年6月22日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 600
- 试验地点
- 1
- 主要终点
- Heart failure (≥ stade B).
研究概览
简要总结
Type 2 diabetes is a risk factor of heart failure and cognitive decline. Heart failure at its early stage is often silent. At present, primary prevention for heart failure is not available. Our aim is to identify diabetic patients at risk of heart failure in order to develop personalized preventive strategies.
Type 2 diabetes is vascular and metabolic risk factor for cognitive decline though a direct lesional effect but also through an interaction with underlying neurodegenerative lesions. Our aim is to identify diabetic patients at risk of cognitive decline in order to develop personalized preventive strategies
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Persons able to understand and object to the information provided.
- •Type 2 diabetic patient free of heart failure ≥stade B
- •Patient affiliated with a social security scheme.
- •Patient agreeing to sign the informed consent form
排除标准
- •Patient with dementia
- •Patient with at least one of the criteria for heart failure ≥stade B
结局指标
主要结局
Heart failure (≥ stade B).
时间窗: at 48 months
次要结局
- Cognitive decline (composite endpoint)(at 48 months)
- Major cardio-neuro-vascular events(at 48 months)
研究者
研究点 (1)
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