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Clinical Trials/NCT06312709
NCT06312709
Active, not recruiting
Not Applicable

teleABLE: Adapting a Behavioral Activation-Based Intervention to Reduce Post-Stroke Sedentary Behavior Using Telehealth (Pilot Randomized Controlled Trial)

University of Minnesota1 site in 1 country90 target enrollmentApril 4, 2024

Overview

Phase
Not Applicable
Intervention
teleABLE (telehealth-delivered Activating Behavior for Lasting Engagement)
Conditions
Stroke
Sponsor
University of Minnesota
Enrollment
90
Locations
1
Primary Endpoint
Between-group difference in change in sedentary behavior
Status
Active, not recruiting
Last Updated
last month

Overview

Brief Summary

The goal of this clinical trial to test whether a remotely delivered behavioral activation-based intervention called "teleABLE" works better than a health education intervention for (1) reducing sitting time and (2) improving health-related quality among adults who were diagnosed with stroke within the past 12 months.

Participants in this study will:

  • Complete questionnaires at Weeks 1, 8, and 24
  • Wear an activPAL monitor at Weeks 1, 8, and 24
  • Participate in the teleABLE intervention (12 sessions) or the health education intervention (6 sessions)
  • Complete an interview at Week 24
Registry
clinicaltrials.gov
Start Date
April 4, 2024
End Date
August 30, 2026
Last Updated
last month
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Age: 18 years or older
  • Diagnosis: Stroke diagnosis ≤12 months prior to study enrollment
  • ≥6 hours of sedentary behavior on a typical weekday (Sedentary Behavior Questionnaire)
  • Able to walk 150 feet or more without physical assistance from another person, with or without assistive device (assessed by Functional Independence Measure, mobility score ≥5)
  • Able to access an electronic device (smartphone, tablet, or computer) that is compatible with a videoconferencing application
  • Able to identify a support person with whom they have a face-to-face interaction at least one time per week.
  • Able and willing to participate fully in the study and provide informed consent

Exclusion Criteria

  • Currently receiving care in an inpatient rehabilitation, transitional care unit, or skilled nursing facility
  • Severe cognitive or communication impairments (inability to respond accurately to complete study telephone screening or complete informed consent)
  • Comorbid neurodegenerative disorder (e.g. Parkinson's disease, multiple sclerosis, amyotrophic lateral sclerosis, myasthenia gravis, dementia, Alzheimer's disease, Huntington's disease, glioblastoma)
  • Comorbid cancer, currently undergoing chemotherapy or radiation treatment
  • Comorbid major depressive disorder (Patient Health Questionnaire-2, score ≥2)
  • Received inpatient treatment or hospitalized for psychiatric condition and/or alcohol or substance abuse within the past 12 months
  • Diagnosis of a terminal illness and/or currently receiving hospice care
  • Currently pregnant or expecting to become pregnant in the next 6 months
  • History of skin sensitivity that precludes the use of medical tape necessary for adherence to activity monitor measure
  • Inability to speak, read, or understand English

Arms & Interventions

teleABLE

Participants meet with a study therapist 2x/week for 6 weeks (12 sessions) to complete behavioral activation focused on adding personally meaningful non-sedentary activities during times when they typically spend sitting. All sessions are delivered remotely using Zoom videoconferencing.

Intervention: teleABLE (telehealth-delivered Activating Behavior for Lasting Engagement)

Health Education

Participants meet with a study therapist 1x/week for 6 weeks (6 sessions) to review fact sheets focused on healthy lifestyles after stroke. All sessions are delivered remotely using Zoom videoconferencing.

Intervention: Health Education

Outcomes

Primary Outcomes

Between-group difference in change in sedentary behavior

Time Frame: Week 0 to Week 8

Change in mean minutes per day spent in prolonged sedentary time (accumulated in bouts of 30 minutes or more) measured using the activPAL micro4 (7-day wear protocol)

Between-group difference in change scores on health-related quality of life

Time Frame: Week 0 to Week 8

European Quality of Life 5-Dimension 5-Level (EuroQOL-5D-5L) change score. The possible range on this tool is -1 (worst) to 1 (best).

Secondary Outcomes

  • Between-group difference in change in sedentary behavior(Week 0 to Week 24)
  • Between-group difference in change scores on health-related quality of life(Week 0 to Week 24)

Study Sites (1)

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