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临床试验/CTRI/2024/12/078534
CTRI/2024/12/078534尚未招募不适用

To Assess The efficacy of bupivacaine Vs levobupivacaine when combined with lignocaine and hyluronidase for peribulbar block in cataract surgery

Hamidia hospital and gandhi medical college bhopal1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2025年1月15日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
80
试验地点
1
主要终点
•To study the onset of sensory and motor block by

研究概览

简要总结

For a perfect and uneventful cataract surgeries, atleast 1 to 1.5 hours time duration is needed for complete akinesia and analgesia to the patients.

In cataract surgery, Peribulbar and Retrobulbar block has gained popularity over general anaesthesia as there is less hemodynamic instability,lessrespiratory depression, better post operative analgesia and less nausea & vomiting with regional anaesthesia, hence safer and more popular than general anaesthesia.

Peribulbar block is a rapid, simple & safe technique but requires larger volume of local anaesthetic solution to produce desired akinesia. The duration of the block depends on type and composition of local anaesthetic mixture injected. Hence, the present study will be carried out on local anaesthetic solution in peribulbar block to find out efficacy, duration, quality of block and side effect if any. The isomer of drugs might prolong the duration of block. So it could be better for cataract surgeries and with a better outcome.

研究设计

研究类型
Observational

入排标准

年龄范围
20.00 Year(s) 至 65.00 Year(s)(—)
性别
All

入选标准

  • ASA I and II prior informed consent schduled for cataract surgery.

排除标准

  • patient refusal highly uncooperative patient history of allergy for local anesthetic agents ASA III and IV.

结局指标

主要结局

•To study the onset of sensory and motor block by

时间窗: will be assessed at baseline 2 mins,5 mins 10 mins 20 mins and 30 mins

Bupivacaine v/s Levobupivacaine with

时间窗: will be assessed at baseline 2 mins,5 mins 10 mins 20 mins and 30 mins

lignocaine and hyaluronidase.

时间窗: will be assessed at baseline 2 mins,5 mins 10 mins 20 mins and 30 mins

•To study the duration of analgesia and akinesia achieved with these drugs.

时间窗: will be assessed at baseline 2 mins,5 mins 10 mins 20 mins and 30 mins

次要结局

  • • To study the occurrence of complications related to Bupivacaine and Levobupivacaine with lignocaine and hyaluronidase(will be assessed at baseline 2 mins,5 mins 10 mins 20 mins and 30 mins)

研究者

发起方
Hamidia hospital and gandhi medical college bhopal
申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

Dr arvind sahu

Gandhi Medical College, Bhopal

研究点 (1)

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