THE ROLE OF CIRCULATING TUMOUR CELLS AS EARLY PREDICTORS OF TUMOUR RECURRENCE AFTER SURGERY FOR HEPATOCELLULAR CARCINOMA
Not Applicable
- Conditions
- Health Condition 1: C220- Liver cell carcinoma
- Registration Number
- CTRI/2023/04/051771
- Lead Sponsor
- MOHAMED RELA
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. All Hepatocellular carcinoma patients who undergo resection or liver transplantation with a curative intent
Exclusion Criteria
1. Non-Hepatocellular carcinoma liver tumours
2. Hepatocellular carcinoma patients who have undergone management with a non-curative intent (TACE/TARE/MWA etc.)
3. Patients not able to follow-up
4. Patients unwilling for the study
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Post-Surgical Recurrence of Hepatocellular carcinoma <br/ ><br>Detected on CTC assay-correlating with image detected recurrenceTimepoint: Day 1, Day 7, Day 14, Day 30, 3 months, 6 months, 9 months, 12 months, 15 months, 18 months, 24 months
- Secondary Outcome Measures
Name Time Method 1. Detect the lead-time between CTC rise and imaging <br/ ><br>2. Prognosticate the risk of recurrence based on the first post-operative week delta-change in CTC after surgeryTimepoint: Day-1, Day-0(intraoperative), Day 1, Day 7, Day 14, Day 30, 3 months, 6 months, 9 months, 12 months, 15 months, 18 months, 24 months