NCT06255301
Completed
N/A
Collection of Ocular Surface Impressions Cytology of the Living Eye From Patients With Dry Eyes or Limbal Stem Cell Deficiency.
Centre Hospitalier Universitaire de Saint Etienne1 site in 1 country300 target enrollmentJanuary 9, 2024
ConditionsEye Diseases
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Eye Diseases
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
- Enrollment
- 300
- Locations
- 1
- Primary Endpoint
- Ocular surface impression cytology collected from patients suffering from dry eye syndrome, limbal stem cell deficiency or other pathologies (control).
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
In order to develop innovative biomarkers for the diagnosis of two ocular surface pathologies, Dry Syndrome (DS) and Limbic Stem Cell Deficiency (LSCD), human cells from the ocular surface will be collected in order to test these biomarkers ex vivo.
Detailed Description
To collect them, cytological fingerprints of the ocular surface are made using filter paper applied to the surface using a commercially available EC (European Conformity)-marked medical device, called EYEPRIM.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patient affiliated or entitled to a social security scheme
- •Age 18 years or older
- •Presenting a Dry Syndrome, a limbic stem cell deficiency (clinical diagnosis) or another pathology (control).
- •Signature of Consent
Exclusion Criteria
- •Major blepharospasm making examination impossible
- •Pregnant women
- •Breastfeeding women
- •Protected Persons
Outcomes
Primary Outcomes
Ocular surface impression cytology collected from patients suffering from dry eye syndrome, limbal stem cell deficiency or other pathologies (control).
Time Frame: day one
Collection of cells from the ocular surface by performing a cytological imprint of the ocular surface
Study Sites (1)
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