EFFICACY OF INTRAUTERINE INSEMINATION IN THE MANAGEMENT OF INFERTILITY.

IUI is one of the most commonly performed treatments for infertile or sub-fertile patients with male factor and consists of instrumental introduction of processed sperm into the uterus via the cervix to deliver motile sperm to the fallopian tubes around ovulation time. In this procedure the sperm sample is centrifuged, washed and kept in the incubator for capacitation prior to insemination into the uterine cavity. This treatment is used for women with patent tubes and considered the most cost-effective initial treatment for unexplained and moderate male factor infertility.  IUI in combination with controlled ovarian hyperstimulation (COH) results in acceptable pregnancy rates per cycle however the overall reported success rates of IUI are variable and ranges from 5-70%. Female age is the most important predictor of IUI success since age has negative impact on ovarian reserve and oocyte quality.  Achieving maximum pregnancy rate following IUI-COH requires a balance between an optimal number of follicles, risk of ovarian hyper-stimulation, and multiple pregnancies. In patients with a large number of follicles growing, conversion from IUI to IVF, avoids cancellation of the cycle and lowers the risk of high order multiple pregnancy.

 AIMS AND OBJECTIVESAims**Efficacy of intrauterine insemination in the management of infertility.**Objectives1.     Show the efficacy of IUI in the treatment of infertility.

2.     To compare the results of couples undergoing IUI with those adopting timed intercourse but using the same stimulation protocol.