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Clinical Trials/NCT04266652
NCT04266652
Unknown
Phase 4

The Effect of Autogenous Tooth Roots for Lateral Alveolar Ridge Augmentation and Staged Implant Placement (A Controlled Clinical Study With Histological Assessment)

Ain Shams University1 site in 1 country14 target enrollmentJanuary 6, 2018
ConditionsAugmentation

Overview

Phase
Phase 4
Intervention
Not specified
Conditions
Augmentation
Sponsor
Ain Shams University
Enrollment
14
Locations
1
Primary Endpoint
Clinical and radiographic assessment of alveolar bone width following autogenous tooth roots augmentation.
Last Updated
5 years ago

Overview

Brief Summary

assess and compare the efficacy and safety of autogenous tooth roots for lateral alveolar ridge augmentation with staged implant placement in comparison to autogenous bone block.

Detailed Description

A total of 14 patients in need of implant therapy and lateral ridge augmentation were allocated to parallel groups receiving either 1) healthy autogenous tooth roots (e.g. retained wisdom or impacted teeth or 2) cortical autogenous bone blocks harvested from the retromolar area. After 26 weeks of submerged healing the horizontal bone gain were assessed both clinically and radiographically. A core biopsy was taken during the implant placement to assess the histology of the newly formed bone.

Registry
clinicaltrials.gov
Start Date
January 6, 2018
End Date
September 30, 2020
Last Updated
5 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Doaa Adel Salah Khattab

Lecturer Periodontology, Faculty of Dentistry

Ain Shams University

Eligibility Criteria

Inclusion Criteria

  • Candidate for lateral ridge augmentation
  • Insufficient bone ridge width at the recipient site for implant placement
  • Sufficient bone height at the recipient site for implant placement
  • Healthy oral mucosa, at least 3 mm keratinized tissue.
  • Presence of wisdom teeth free from periapical infection.
  • Missing maxillary or mandibular tooth with moderate horizontal defect (4-8) according to cologne classification

Exclusion Criteria

  • Patients are systemically free according to Modified Cornell Medical Index 2) smokers patients. 3) Pregnant or lactating women.

Outcomes

Primary Outcomes

Clinical and radiographic assessment of alveolar bone width following autogenous tooth roots augmentation.

Time Frame: 6 months postoperatively

Secondary Outcomes

  • Histological analysis of remodeled autogenous bone roots 4 months following horizontal ridge augmentation. Histological analysis of remodeled autogenous bone roots 4 months following horizontal ridge augmentation.(6 months postoperatively)

Study Sites (1)

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