Continuous Erector Spinae Plane Local Anesthetic Infusion for Postoperative Analgesia in Pediatric Patients Undergoing Nephrectomy: Randomized Controlled Study
Overview
- Phase
- Phase 3
- Intervention
- Bupivacaine Hydrochloride
- Conditions
- Pediatric Cancer
- Sponsor
- Assiut University
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- total amount of opioid consumption in milligram
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
The aim of this study is to evaluate the analgesic efficacy of erector spinae plane block in pediatric cancer patients undergoing open nephrectomy
Detailed Description
* Sixty patients will be included in this prospective randomized study. The patients will be allocated into two groups: the ESPB group (group E, n = 30) and the tramal group (group T, n =30). * All patients will receive standard general anesthesia. Ultrasound-guided ESPB will be performed to group erector spinae plane block
Investigators
Fatma Adel El sherif,MD
Associated professor of anesthesia,ICU and pain management
Assiut University
Eligibility Criteria
Inclusion Criteria
- •Physical status ASA II.
- •Patients (age 2-7yrs) scheduled for open nephrectomy for malignant kidney tumors
Exclusion Criteria
- •History of psychological disorders.
- •Known sensitivity or contraindication to local anesthetics.
- •Localized infection at the site of block.
- •patients with coagulopathy or an (INR ≥ 2)
Arms & Interventions
Erector spinae group
patient will be placed in a sitting position under complete aseptic condition and a cover sheath will be used for the ultrasound probe with an appropriate amount of lubricating gel applied on the probe, a high-frequency linear ultrasound transducer will be placed in a longitudinal orientation 3 cm lateral to the L3 spinous process. This should reveal three muscles superficial to the hyperechoic transverse process shadow as follows: trapezius, rhomboid major, and erector spinae.
Intervention: Bupivacaine Hydrochloride
Opioid GROUP
Patient in group T will intravenously administrate dose of 1 mg/kg/8hr tramal ( opioid) to be increased upon patient needs up to 2mg/kg/6hr as rescue analgesic.
Intervention: Tramadol hydrochloride
Outcomes
Primary Outcomes
total amount of opioid consumption in milligram
Time Frame: 48 hours
total amount of opioid consumption in the frist 48hours postoperative