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QRS Microfragmentation in ECG as Predictor of Mortality and Morbidity - a Retrospective Analysis

Completed
Conditions
Risk Stratification
Registration Number
NCT06011590
Lead Sponsor
Medical University Innsbruck
Brief Summary

Over the past decades, several ECG-based parameters have been identified as independent predictors of worsened prognosis in affected patients. In addition to visual assessment of morphology, methods of computer-based machine ECG analysis have gained importance in recent years. These methods allow the detection of systemic abnormalities in ECGs that are not visible to the naked eye. An example of this is provided by the so-called "QRS microfragmentations".

The aim of this evaluation is to retrospectively collect all established as well as new quantitative and qualitative ECG parameters (such as QRS microfragmentation) in a large patient collective. Subsequently, after characterization of the patients, an independent multivariate risk prediction model should be developed based on computer-based ECG analysis using maschnine learning algorithms.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
150000
Inclusion Criteria
  • Patients who presented to the Department of Internal Medicine at the Medical University in Innsbruck between 01.01.2000 and 31.07.2022 and received an ECG recording as part of routine clinical practice.
  • Age ≥ 18 years
  • Residence in Austria
Exclusion Criteria
  • Insuffizient ECG Recording quality

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
All cause mortalitybetween 01.01.2000 and 31.07.2022

Death of any cause

Secondary Outcome Measures
NameTimeMethod
Hospitalizationbetween 01.01.2000 and 31.07.2022

Unplanned Hospitalization

Lenght of hospital staybetween 01.01.2000 and 31.07.2022

Lenght of hospital stay

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