Evaluation of pretreatment with three different types of drugs in providing relieffrom pain and withdrawal movements on injection of an Anaesthetic drug at the time of induction
Not Applicable
Not yet recruiting
- Conditions
- Patients aged 18-65 years, of either sex, ASA grade I and II, BMI less than or equal to 30 kg/m2 , undergoingelective surgical procedures under general anaesthesia with endotracheal intubation.
- Registration Number
- CTRI/2018/03/012482
- Lead Sponsor
- Vardhaman Mahavir Medical College and Safdarjung Hospital
- Brief Summary
1.To study the degree of alleviation of pain and withdrawal movements, with propofol injection during induction of anaesthesia, using lignocaine, dexmedetomidine or ketamine as pretreatment.
2.To study the variations in haemodynamic parameters.
HYPOTHESIS : Pretreatment with dexmedetomidine would be comparable to ketamine and lignocaine in providing relief from pain and withdrawal movements associated with propofol injection during induction of anaesthesia.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 135
Inclusion Criteria
- ASA grade I & II 2.
- BMI less than or equal to 30 kg/m2 3.
- undergoing elective surgical procedures under general anaesthesia with endotracheal intubation.
Exclusion Criteria
- History of pulmonary, renal, hepatic, endocrine, neurological or cardiovascular disease(including hypertension, those on beta blockers or digitalis),patients on any sedatives, anxiolytics or analgesics, history of drug abuse and psychiatric illness, known hypersensitivity to the study drugs.
- Pregnant and nursing females and emergency surgical procedures.
- Subjects with anticipated difficulty in venous access.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To study the degree of alleviation of pain and withdrawal movements, with propofol injection At the time of induction. during induction of anaesthesia, using lignocaine, dexmedetomidine or ketamine as At the time of induction. pretreatment. At the time of induction.
- Secondary Outcome Measures
Name Time Method To study the variations in haemodynamic parameters. At the time of induction, preintubation , intubation and post intubation.
Trial Locations
- Locations (1)
Vardhaman Mahavir Medical College and Safdarjung Hospital
🇮🇳South, DELHI, India
Vardhaman Mahavir Medical College and Safdarjung Hospital🇮🇳South, DELHI, IndiaDr Karishma BatraPrincipal investigator9899902047karishmabatra05@gmail.com