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临床试验/NCT05221736
NCT05221736Unknown不适用

Comparison Between Ultrasound-Guided Ethanol Sclerotherapy (UGES) & Surgical Excision in Management of Warthin Tumor of Parotid Gland.

Assiut University2 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2022年5月1日最近更新:
适应症

试验速览

阶段
不适用
入组人数
20
试验地点
2
主要终点
Primary (main):

研究概览

简要总结

Comparison between Ultrasound-Guided Ethanol Sclerotherapy (UGES) & surgical excision in management of warthin tumor of parotid gland.

详细描述

Warthin tumor (also known as cystadenolymphoma), is a benign and frequent salivary gland neoplasm.

It represents about 2% to 15% of all primary epithelial tumors of the parotid gland.

Warthin tumor is histologically characterized by a dense lymphoid stroma and a double layer of oncocytic epithelium with a papillary and cystic architectural pattern.

Its etiology: remains controversial. Incidence: It is the second most frequent benign neoplasm of the salivary glands after pleomorphic adenoma. Pathophysiology: Initially, Hildebrand proposed that the lesion may be remnants of the branchial pouches and a variant of the lateral cervical cyst. Later, Albrech and Artz proposed the heterotropic origin of Warthin tumor from the neoplastic proliferation of salivary gland ducts present within intra- or para-parotid nodes. Histopathology: Grossly, Warthin tumor is a well-circumscribed spherical to oval mass. On cut section, there are solid areas and multiple cysts with papillary projections.

Cytology: Smears characteristically show oncocytic epithelial cells without atypia admixed with polymorphous lymphocytes and cellular debris.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Treatment
盲法
None

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • All new cases presented with benign parotid cyst and diagnosed as Warthin tumour in the parotid gland.

排除标准

  • Other Parotid gland tumours e.g. solid tumours, malignant tumours and other suspicious tumours.

结局指标

主要结局

Primary (main):

时间窗: 1 year

Rate of curability in each group

次要结局

  • Secondary (subsidiary):(1 week)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

kerolos nashaat hosny

assistant lecturer

Assiut University

研究点 (2)

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