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Clinical Trials/NCT05221736
NCT05221736UnknownNot Applicable

Comparison Between Ultrasound-Guided Ethanol Sclerotherapy (UGES) & Surgical Excision in Management of Warthin Tumor of Parotid Gland.

Assiut University2 sites in 1 country20 target enrollmentStarted: May 1, 2022Last updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Enrollment
20
Locations
2
Primary Endpoint
Primary (main):

Study Overview

Brief Summary

Comparison between Ultrasound-Guided Ethanol Sclerotherapy (UGES) & surgical excision in management of warthin tumor of parotid gland.

Detailed Description

Warthin tumor (also known as cystadenolymphoma), is a benign and frequent salivary gland neoplasm.

It represents about 2% to 15% of all primary epithelial tumors of the parotid gland.

Warthin tumor is histologically characterized by a dense lymphoid stroma and a double layer of oncocytic epithelium with a papillary and cystic architectural pattern.

Its etiology: remains controversial. Incidence: It is the second most frequent benign neoplasm of the salivary glands after pleomorphic adenoma. Pathophysiology: Initially, Hildebrand proposed that the lesion may be remnants of the branchial pouches and a variant of the lateral cervical cyst. Later, Albrech and Artz proposed the heterotropic origin of Warthin tumor from the neoplastic proliferation of salivary gland ducts present within intra- or para-parotid nodes. Histopathology: Grossly, Warthin tumor is a well-circumscribed spherical to oval mass. On cut section, there are solid areas and multiple cysts with papillary projections.

Cytology: Smears characteristically show oncocytic epithelial cells without atypia admixed with polymorphous lymphocytes and cellular debris.

Study Design

Study Type
Interventional
Allocation
Na
Intervention Model
Single Group
Primary Purpose
Treatment
Masking
None

Eligibility Criteria

Ages
18 Years to 80 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • All new cases presented with benign parotid cyst and diagnosed as Warthin tumour in the parotid gland.

Exclusion Criteria

  • Other Parotid gland tumours e.g. solid tumours, malignant tumours and other suspicious tumours.

Outcomes

Primary Outcomes

Primary (main):

Time Frame: 1 year

Rate of curability in each group

Secondary Outcomes

  • Secondary (subsidiary):(1 week)

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

kerolos nashaat hosny

assistant lecturer

Assiut University

Study Sites (2)

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