Comparison Between Ultrasound-Guided Ethanol Sclerotherapy (UGES) & Surgical Excision in Management of Warthin Tumor of Parotid Gland.
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Assiut University
- Enrollment
- 20
- Locations
- 2
- Primary Endpoint
- Primary (main):
Study Overview
Brief Summary
Comparison between Ultrasound-Guided Ethanol Sclerotherapy (UGES) & surgical excision in management of warthin tumor of parotid gland.
Detailed Description
Warthin tumor (also known as cystadenolymphoma), is a benign and frequent salivary gland neoplasm.
It represents about 2% to 15% of all primary epithelial tumors of the parotid gland.
Warthin tumor is histologically characterized by a dense lymphoid stroma and a double layer of oncocytic epithelium with a papillary and cystic architectural pattern.
Its etiology: remains controversial. Incidence: It is the second most frequent benign neoplasm of the salivary glands after pleomorphic adenoma. Pathophysiology: Initially, Hildebrand proposed that the lesion may be remnants of the branchial pouches and a variant of the lateral cervical cyst. Later, Albrech and Artz proposed the heterotropic origin of Warthin tumor from the neoplastic proliferation of salivary gland ducts present within intra- or para-parotid nodes. Histopathology: Grossly, Warthin tumor is a well-circumscribed spherical to oval mass. On cut section, there are solid areas and multiple cysts with papillary projections.
Cytology: Smears characteristically show oncocytic epithelial cells without atypia admixed with polymorphous lymphocytes and cellular debris.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 80 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •All new cases presented with benign parotid cyst and diagnosed as Warthin tumour in the parotid gland.
Exclusion Criteria
- •Other Parotid gland tumours e.g. solid tumours, malignant tumours and other suspicious tumours.
Outcomes
Primary Outcomes
Primary (main):
Time Frame: 1 year
Rate of curability in each group
Secondary Outcomes
- Secondary (subsidiary):(1 week)
Investigators
kerolos nashaat hosny
assistant lecturer
Assiut University
