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Clinical Trials/NCT01454570
NCT01454570
Completed
N/A

The ReWalk Exoskeletal Walking System for Persons With Paraplegia

James J. Peters Veterans Affairs Medical Center1 site in 1 country19 target enrollmentFebruary 2011
ConditionsParaplegia

Overview

Phase
N/A
Intervention
Not specified
Conditions
Paraplegia
Sponsor
James J. Peters Veterans Affairs Medical Center
Enrollment
19
Locations
1
Primary Endpoint
Count to Achieve Mobility Skills
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

It is well appreciated that an extreme sedentary lifestyle from paralysis, contributes to many secondary medical problems such as diabetes and insulin resistance, obesity, constipation, poor blood pressure regulation, cardiovascular disease, reduced quality of life, and more. The ReWalk-I exoskeleton walking device permits investigation of the potential benefits of frequent upright posture and walking on many of the secondary consequences of spinal cord injury. The researchers are investigating the ability of persons with paraplegia to learn to stand and walk with the ReWalk-I and the effects of being upright and walking on several of these secondary medical consequences of spinal cord injury.

Detailed Description

Potential participants will be pre-screened with the inclusion criteria for eligibility. The informed consent process will begin for those participants who have been determined to meet the inclusion criteria. After the potential participant's signed consent has been provided, further evaluations for eligibility will be performed (e.g., there are several medical and physical exclusion criteria). Those potential participants who meet both the inclusion and exclusion criteria will be eligible to enroll into the ReWalk-I study. Baseline evaluations and personalized measurements for fitting to the ReWalk-I will be performed over one week, before the training sessions begin. The ReWalk sessions will consist of a Learning Phase (12 sessions in 4 weeks) and a Training Phase (18 sessions in 6 weeks). These times may vary by each participant's ReWalk learning curve. Training will begin with sit-to-stand, stand-to-sit, and standing balance activities. Progression to walking will occur as skills advance. Each session will be an average 50 minutes, with 3 sessions per week. The skills to be learned include 1) sit-to-stand, 2) stand-to-sit, 3) 2-arm standing balance, 4) 1-arm standing balance, 5) walking, and 6) stair climbing. The study evaluations will be repeated after the Learning Phase, after the Training Phase and 1-month post training follow-up.

Registry
clinicaltrials.gov
Start Date
February 2011
End Date
August 8, 2015
Last Updated
5 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
James J. Peters Veterans Affairs Medical Center
Responsible Party
Principal Investigator
Principal Investigator

Ann M. Spungen, EdD

Associate Director of CoE / Health Science Specialist

James J. Peters Veterans Affairs Medical Center

Eligibility Criteria

Inclusion Criteria

  • Males or females with paraplegia
  • Duration of SCI \>6 months
  • Ages 18 to 65 y
  • Height 160 to 190cm (63-75in or 5'3" to 6'3")
  • Weight \<100kg (\<220 lb)
  • Ability to give informed consent

Exclusion Criteria

  • Diagnosis of neurological injury other than SCI including:
  • Multiple sclerosis (MS)
  • Cerebral Palsy (CP)
  • Amyotrophic lateral sclerosis (ALS)
  • Traumatic Brain injury (TBI)
  • Spina bifida
  • Parkinson's disease (PD)
  • Other neurological condition that the study physician considers in his/her clinical judgment to be exclusionary
  • Severe concurrent medical disease, illness or condition
  • Recent lower extremity fracture within the past 2 years;

Outcomes

Primary Outcomes

Count to Achieve Mobility Skills

Time Frame: ReWalk training at 4 and 12 weeks, and 1-month follow-up

1. To determine efficacy for mobility defined as the ability to perform the following with the ReWalk-I exoskeletal system, without staff assistance: 1. Sit-to-stand, 2. Stand-to-sit, 3. Standing balance for 1 minutes with both crutches, 4. Standing balance for 30 seconds with one crutch, 5. Ten meter walk in ≤2 minutes, 6. Walk ≥30 meters in 6-minutes, and 7. Ascend, turn around and descend 4 stairs in 5 minutes.

Study Sites (1)

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