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NOVA22007 0.05% and 0.1% Cyclosporine Versus Vehicle for the Treatment of Dry Eye

Phase 2
Completed
Conditions
Dry Eye
Interventions
Drug: NOVA22007 ''Cyclosporine''
Drug: vehicle/placebo
Registration Number
NCT00739349
Lead Sponsor
Santen SAS
Brief Summary

Study is to assess the safety and efficacy of NOVA22007 0.05% and 0.1% Cyclosporine Ophthalmic Cationic Emulsions QD compared to vehicle for the treatment of the signs and symptoms of dry eye after a 3 month treatment period.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
132
Inclusion Criteria
  • Male and female 18 years and older
  • Diagnosis of dry eye in both eyes
Exclusion Criteria
  • Contraindications to the use of the study medications
  • Known allergy or sensitivity to the study medications or their components
  • Female currently pregnant, nursing, or planning a pregnancy; or woman who has a positive pregnancy test
  • Have participated in an investigational drug or device study within 30 days of Visit 1

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
2NOVA22007 ''Cyclosporine''Cyclosporine 0.1%
1NOVA22007 ''Cyclosporine''Cyclosporine 0.05%
3vehicle/placebovehicle/placebo
Primary Outcome Measures
NameTimeMethod
Assess the safety and efficacy of two doses of NOVA22007 0.05% and 0.1% Cyclosporine Ophthalmic EmulsionsApproximately 13 weeks
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Central Maine Eye Care, PA

🇺🇸

Lewiston, Maine, United States

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