Pilot Study for the Early Detection of Chronic Kidney Disease, Non-Dialysis Objective (NDO).

• Conditions: Chronic Kidney Disease (CKD)
• Interventions: Diagnostic Test: albumin creatinine ratio

• Registration Number: NCT06447038
• Lead Sponsor: Hospital Universitario de Burgos

Brief Summary

Chronic kidney disease (CKD) is a significant public health problem worldwide, affecting more than 10% of the Spanish population. Early detection is considered a top healthcare priority to establish strategies for preventing progression to more advanced stages of the disease and its complications. Additionally, CKD is associated with high comorbidity, poor prognosis, and substantial resource consumption within the healthcare system. In this context, albuminuria may be a more sensitive marker of CKD than reduced glomerular filtration rate (GFR), and it is also considered an indicator of not only renal damage but also \"systemic damage\" (generalized endothelial dysfunction, arterial remodeling, and increased cardiovascular risk) beyond the kidney. Furthermore, the reduction of proteinuria/albuminuria is clearly associated with a slower progression of CKD, making its reduction a therapeutic goal as well. Given this importance, this protocol aims to determine the urine albumin/creatinine ratio in all patients over 18 years old who visit their primary care physician in the province of Burgos, Spain, and require a blood test related to their reason for consultation.

Detailed Description

This is a protocol in which we seek to identify those patients with alterations incipient renal failure by determining the albumin/creatinine ratio in urine, test that is currently performed routinely in different groups of patients. By For this reason, the implementation of the non-dialysis objective protocol hopes to be implemented standardized form in patients who go to their primary attention doctor in the province of Burgos to later be extended to the entire Castilla y Leon community.

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Study Timeline

• Study Start: 2024-02-01
• Status Verified: 2024-06
• Study First Submitted: 2024-06-03
• Study First Submitted QC: 2024-06-03
• Last Update Submitted: 2024-06-03
• Study First Posted: 2024-06-06
• Last Update Posted: 2024-06-06
• Primary Completion: 2024-10
• Study Completion: 2024-12

Recruitment & Eligibility

• Status: ENROLLING_BY_INVITATION
• Sex: All
• Target Recruitment: 10000

Inclusion Criteria

• Minimum age 18 years

Exclusion Criteria

• Age less than 18 years

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Population	albumin creatinine ratio	Population of the city of Burgos \> 18 years old.

Primary Outcome Measures

Name	Time	Method
Albumin creatinine ratio.	01/02/2024 al 01/12/2024	Determination of albuminuria in urine.

Trial Locations

Locations (1)

Maria J Izquierdo; 🇪🇸 Burgos, Spain