A Cognitive Behavioral Therapy-Based Text Messaging Intervention for Methamphetamine Dependence
Trial Snapshot
- Phase
- Phase 1
- Status
- Completed
- Sponsor
- New Leaf Treatment Center
- Enrollment
- 25
- Locations
- 1
- Primary Endpoint
- Feasibility of the intervention in methamphetamine users
Study Overview
Brief Summary
This Phase I, randomized, 22-day crossover study seeks to improve treatment outcomes for methamphetamine-dependent subjects by developing a cognitive behavioral therapy (CBT)- based short message service (SMS) text messaging intervention as an adjunct to CBT group therapy.
Detailed Description
Psychosocial therapies for methamphetamine (MA) addiction all have limited effectiveness, and patients treated for MA dependence have a high rate of relapse. Additionally, there are no currently approved medications for MA dependence. Thus, a significant need exists for add-on therapy for treatment of MA addiction. CBT-based text messaging could serve as a real-time intervention when craving and risk of MA use are high and patients are not in the clinic. It could further serve to reinforce CBT group therapy. If found efficacious, fully-automated CBT-based text messaging would be a relatively inexpensive adjunctive therapy that could be readily scaled up for use in a large number of patients. Additionally, this type of text messaging intervention also could be tailored to individual users, which may enhance its efficacy. This Phase I randomized crossover study will evaluate the feasibility and preliminary efficacy of CBT-based text messages in conjunction with CBT group therapy delivered over a 22-day period in MA users in the San Francisco Bay Area.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Crossover
- Primary Purpose
- Treatment
- Masking
- Single (Investigator)
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Main inclusion criterion:
- •English-speaking adults who are currently seeking treatment for methamphetamine addiction
Exclusion Criteria
- Not provided
Arms & Interventions
CBT-based text messages - Week 1 or 3
One week CBT-based text messages followed by a 1-week washout period (Week 2)
Intervention: Text messages (Behavioral)
Placebo text messages - Week 3 or 1
Intervention: Text messages (Behavioral)
Outcomes
Primary Outcomes
Feasibility of the intervention in methamphetamine users
Time Frame: 22 days
Subjects will respond to \>50% of text messaging inquiries (about the usefulness of the messages, maximum degree of craving, and whether they have used that day).
Secondary Outcomes
- Acceptability of the intervention in methamphetamine users(22 days)