Evaluation of the Effectiveness of Oxygen Reserve Index Monitoring During Pre-oxygenation in Obese Patients
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- Evaluation of the Effectiveness of Oxygen Reserve Index Monitoring During Pre-oxygenation in Obese Patients
Study Overview
Brief Summary
In obese patients, the risk of perioperative complications such as rapid desaturation, atelectasis, difficult mask ventilation, difficult intubation, and hypoxia is higher compared to the normal population. Therefore, preoxygenation is even more critical in the obese patient group. In clinical practice, ETO2 is used as a practical indicator to evaluate sufficient oxygenation during preoxygenation. The Oxygen Reserve Index (ORiⓇ) is a new oxygenation monitoring parameter that is continuously and non-invasively measured by a specialized pulse oximetry device (Masimo, Irvine, CA).The primary objective of the investigators was to observe the correlation between ORIⓇ monitoring and ETO₂ during preoxygenation in obese patients.The secondary objective of the investigators was to evaluate the correlation of ORIⓇ with SpO₂ and PaO₂ in this patient population.
Detailed Description
Obesity is a chronic, progressive, and recurrent disease characterized by abnormal fat accumulation that adversely affects health and increases morbidity and mortality.
According to World Health Organization (WHO) data, the prevalence of obesity among adults aged 18 years and older is reported to be 16%.
Obese patients have an increased risk of perioperative complications compared to the general population, including rapid desaturation, atelectasis, difficult mask ventilation, difficult intubation, and hypoxia.
Therefore, preoxygenation is particularly important in obese patient populations.
The goal of preoxygenation is to maximize the duration during which the patient can tolerate apnea, thereby providing the anesthesiologist with crucial time to secure the airway in cases of planned or unanticipated "cannot ventilate, cannot intubate" scenarios.
Study Design
- Study Type
- Observational
- Observational Model
- Other
- Time Perspective
- Cross Sectional
Eligibility Criteria
- Ages
- 18 Years to 75 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Patients with a body mass index (BMI) >35 kg/m² scheduled for elective surgery
- •ASA (American Society of Anesthesiologists) physical status classification I-III
- •Patients aged 18 years and older
Exclusion Criteria
- •Patients with ASA physical status classification IV-V,
- •Psychiatric disorders
- •Severe cardiac arrhythmias
- •Patients with an ejection fraction below 30%
- •Chronic obstructive pulmonary disease (COPD)
- •Those receiving home oxygen therapy
- •Patients requiring supraglottic airway devices, and emergency cases
Outcomes
Primary Outcomes
Evaluation of the Effectiveness of Oxygen Reserve Index Monitoring During Pre-oxygenation in Obese Patients
Time Frame: During 5-minute preoxygenation
Non-invasive ORiⓇ values and ETO₂ levels measured every minute during tidal volume breathing in the preoxygenation period will be analyzed for correlation.
Secondary Outcomes
- Correlation between ORiⓇ and arterial oxygen pressure (PaO₂) at multiple time points after intubation(30, 60, 90, and 120 minutes after intubation)
- Correlation between ORiⓇ and peripheral oxygen saturation (SpO₂) at multiple time points after intubation(30, 60, 90, and 120 minutes after intubation)
Investigators
Irem Caner
Research Assistant
Kocaeli University