Research into Antipsychotic Discontinuation and Reduction (RADAR): a randomised controlled trial

niversity College London0 个研究点目标入组 253 人开始时间: 2017年2月7日最近更新: 2023年10月16日

适应症

试验速览

2019 Protocol article in https://pubmed.ncbi.nlm.nih.gov/31780589/ protocol (added 27/10/2020) 2023 Results article in https://pubmed.ncbi.nlm.nih.gov/37778356/ (added 02/10/2023)

•1. Aged over 18 years
•2. A clinical and/or ICD10 diagnosis of schizophrenia, schizoaffective disorder, delusional disorder or other non-affective psychosis
•3. More than one previous episode of relapse or psychotic exacerbation, or a single episode lasting more than one year
•4. Taking antipsychotic medication

•1. Participant lacks capacity to consent to the trial
•2. Participant has insufficient command of spoken English to understand trial procedures
•3. Participant subject to a Community Treatment Order (CTO) that includes a requirement to take antipsychotic medication
•4. Clinician considers there will be a serious risk of harm to self or others
•5. Participant has been admitted to hospital or had treatment from the Home Treatment or Crisis Team within the last month
•6. Females who have a confirmed pregnancy
•7. Females who are breast-feeding
•8. Involvement in another IMP trial
•9. No contraindications to continuing on antipsychotic medication

发起方

niversity College London