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Clinical Trials/ISRCTN90298520
ISRCTN90298520
Completed
未知

Research into Antipsychotic Discontinuation and Reduction (RADAR): a randomised controlled trial

niversity College London0 sites253 target enrollmentFebruary 7, 2017
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ConditionsSchizophreniaMental and Behavioural Disorders

Overview

Phase
未知
Intervention
Not specified
Conditions
Schizophrenia
Sponsor
niversity College London
Enrollment
253
Status
Completed
Last Updated
2 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

2019 Protocol article in https://pubmed.ncbi.nlm.nih.gov/31780589/ protocol (added 27/10/2020) 2023 Results article in https://pubmed.ncbi.nlm.nih.gov/37778356/ (added 02/10/2023)

Registry
who.int
Start Date
February 7, 2017
End Date
March 10, 2022
Last Updated
2 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
niversity College London

Eligibility Criteria

Inclusion Criteria

  • •1\. Aged over 18 years
  • •2\. A clinical and/or ICD10 diagnosis of schizophrenia, schizoaffective disorder, delusional disorder or other non\-affective psychosis
  • •3\. More than one previous episode of relapse or psychotic exacerbation, or a single episode lasting more than one year
  • •4\. Taking antipsychotic medication

Exclusion Criteria

  • •1\. Participant lacks capacity to consent to the trial
  • •2\. Participant has insufficient command of spoken English to understand trial procedures
  • •3\. Participant subject to a Community Treatment Order (CTO) that includes a requirement to take antipsychotic medication
  • •4\. Clinician considers there will be a serious risk of harm to self or others
  • •5\. Participant has been admitted to hospital or had treatment from the Home Treatment or Crisis Team within the last month
  • •6\. Females who have a confirmed pregnancy
  • •7\. Females who are breast\-feeding
  • •8\. Involvement in another IMP trial
  • •9\. No contraindications to continuing on antipsychotic medication

Outcomes

Primary Outcomes

Not specified

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