The Safety and Efficacy of 1064-nm Picosecond Laser 1064 With Microlens Array for Pore Tightening; a Pilot Study
Overview
- Phase
- Not Applicable
- Sponsor
- Mahidol University
- Enrollment
- 26
- Locations
- 1
- Primary Endpoint
- Change in pore size by Antera 3D image
Overview
Brief Summary
The objective of this study is to evaluate the safety and efficacy of 1064-nm Picosecond laser 1064 With Microlens Array for Pore tightening.
Detailed Description
The Safety and Efficacy of Picosecond laser 1064 Nanometers With Microlens Array for Pore tightening; a Pilot Study Primary outcome : pore size Secondary outcome : side effect, patient satisfaction, global evaluation the patient recieved laser treament once a month for 3 months and then follow up after last treatment at 1, 3 ,6 month
Enlarged facial pores is one of the skin signs in photoaging. There are 3 major clinical causes of enlarged facial pores: highs sebum excretion, decreased elasticity around pores and increased hair follicle volume. Possible causative factors of enlarged facial pores include many exogenous and endogenous factors include genetic predisposition, seborrhea and chronic ultraviolet light exposure. Picosecond laser are new device which has been used in skin rejuvenation. The main mechanism of action is laser induced optical breakdown (LIOB).
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 25 Years to 40 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Both male and female age 25-40 years
- •No underlying disease
Exclusion Criteria
- •History of retinoid or other keratolytic drugs used within 6 months before enrolled
- •History of keloid
- •photosensitivity
- •Immunocompromised host
Outcomes
Primary Outcomes
Change in pore size by Antera 3D image
Time Frame: change from baseline in pore size at 6 months
Secondary Outcomes
No secondary outcomes reported
Investigators
Woraphong Manuskiatti, M.D.
Professor
Mahidol University