Mobilization With Movement Versus Joint-Specific Manipulation in De Quervain's Tenosynovitis

Not Applicable

Completed

• Conditions: Tenosynovitis

• Registration Number: NCT06918158
• Lead Sponsor: Riphah International University

Brief Summary

A comparative study on the effectiveness of mobilization with movement (MWM) versus joint-specific manipulation (JSM) in patients with De Quervain's tenosynovitis typically aims to assess how each technique impacts pain relief and functional improvement. De Quervain's tenosynovitis is an inflammation of the tendons around the thumb and wrist, often causing pain, swelling, and difficulty in performing everyday tasks. The study would likely compare the two interventions by measuring pain levels, range of motion, and overall functional outcomes before and after treatment. MWM involves applying specific, controlled movements while the patient is actively engaging in their joint motion, targeting the tissue's mobility and reducing pain. JSM, on the other hand, focuses on manipulating the joint directly to restore normal function, specifically targeting the wrist and thumb regions affected by the condition.

Detailed Description

A comparative study on the effectiveness of Mobilization with Movement (MWM) versus Joint-Specific Manipulation (JSM) in patients with De Quervain's Tenosynovitis would delve deeper into the physiological mechanisms and clinical outcomes associated with each technique, providing valuable evidence for therapeutic decision-making. De Quervain's Tenosynovitis is a condition characterized by the inflammation of the tendons at the base of the thumb, particularly affecting the abductor pollicis longus and extensor pollicis brevis tendons. This condition is commonly caused by repetitive strain, overuse, or trauma, leading to pain, swelling, and restricted movement, which significantly impacts the patient's daily activities.

Study Timeline

• Study Start: 2025-02-17
• Primary Completion: 2025-02-17
• Study Completion: 2025-02-17
• Study First Submitted: 2025-02-20
• Status Verified: 2025-04
• Study First Submitted QC: 2025-04-07
• Study First Posted: 2025-04-09
• Last Update Submitted: 2025-04-24
• Last Update Posted: 2025-04-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

o Patients clinically diagnosed with De Quervain's tenosynovitis

• Age between 25-45 years.
• Positive Finkelstein test.
• Pain over the first dorsal compartment.
• Limited wrist and thumb function.
• Willingness to take part and adhere to the study's guidelines.

Exclusion Criteria

Participants fall in this category would be excluded of the study.

• Previous surgery of wrist or thumb.
• Presence of neurological symptoms like numbness, weakeness.
• Rheumatological conditions like rheumatoid arthritis.
• Pregnancy.
• Presence of wrist fracture or osteoporosis.
• Carpel tunnel syndrome.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Pain Reduction - Measured using the Numeric Pain Rating Scale (NPRS) (0-10 scale).	6 Months	Pain intensity will be assessed using the Numeric Pain Rating Scale (NPRS), a validated tool where participants rate their pain on a scale from 0 no pain to 10 worst possible pain.

Secondary Outcome Measures

Name	Time	Method
Wrist Function - Assessed with the Patient-Rated Wrist Evaluation (PRWE) (0-100 scale).	6months	Functional wrist use will be assessed using the Patient-Rated Wrist Evaluation (PRWE), which evaluates pain and disability on a 100-point scale, with higher scores indicating greater impairment. Clinical signs will be assessed using Finkelstein's Test, a standard diagnostic test for De Quervain's tenosynovitis, recorded as positive or negative. Data will be analyzed using pre- and post-intervention comparisons within and between groups to determine the effectiveness of each intervention.

Trial Locations

Locations (1)

Riphah international University Malakand Campus; 🇵🇰 Malakand, KPK, Pakistan