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Effect of Night Time Antihypertensive on Blood Pressure pattern in CKD III-IV: A Randomized Controlled Trial

Not Applicable
Completed
Conditions
Health Condition 1: null- chronic kidney disease patient
Registration Number
CTRI/2018/01/011581
Lead Sponsor
IPGMER snd SSKM Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
75
Inclusion Criteria

1.MDRD eGFR <= 60 ml/min/1.73 m2, irrespective of underlying NKD

2.Patients of either sex who were 18 years of age or older are eligible.

3.Patients on antihypertensives taking >= 1 drug(s) of which at least 1 dose is being taken in morning or afternoon

4.Patients should be ambulatory

Exclusion Criteria

1.Suspicion of secondary hypertension, other than CKD.

2.Recent stroke (occurring within the previous 3 months).

3.Recent acute myocardial infarction.

4.Recent hospitalization for heart failure

5.Recent revascularization or planned cardiovascular intervention

6.MDRD eGFR <15 ml/min/1.73 m2 or dialysis requiring

7.Uncontrolled Hypertension (systolic BP >150 mmHg or diastolic BP >90mmHg)

8.Pregnancy

9.Atrial fibrillation

Refusal to undergo repeated follow up visits and ambulatory blood pressure monitoring.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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