The effect of intra-dialytic combined strength-endurance training and melatonin supplementation on biochemical, immune and physiological responses (renal and cardiovascular function), physical capacity and quality of sleep in hemodialysis patients
Phase 3
- Conditions
- Kidney Disease
- Registration Number
- PACTR202005770507528
- Lead Sponsor
- Research Laboratory molecular bases of human pathology LR19ES13 Faculty of medicine of Sfax
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 45
Inclusion Criteria
Patients on stable dialysis treatment (> 3 months on hemodialysis with adequate dialysis efficiency) (4 h / day, 3 days / week).
-Aged between 20 and 60.
-Body mass index (BMI) (kg·m - 2) between 18.5 and 24.9
Exclusion Criteria
The development of a serious condition requiring hospitalization or preventing exercise.
-Participation in a physical rehabilitation program during the past year.
- Orthopedic problems
- Presence of chronic respiratory and cardiac diseases.
-Thrombosis
-Ischemic heart disease
- Uncontrolled hypertension
- Severe dyspnea
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The height and body mass, body mass index
- Secondary Outcome Measures
Name Time Method <br>- immune function and inflammation<br>- oxidative stress<br>- muscle damage<br>- hemodynamic balance<br>-vascular function<br>-Postural stability<br>- Isokinetic muscle strength <br>- Aerobic capacity<br>- Quality of life<br>- Psychological state (anxiety and depression)<br>- The quality of slee