ACTRN12612000703808
Completed
未知
A cross-sectional cohort to assess the age-related changes to the function and morphology of the meibomian glands and the association of these changes to symptomatology in healthy people aged between 25 and less than 65 years of age
Brien Holden Vision Institute0 sites200 target enrollmentJuly 2, 2012
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Meibomian gland dysfunction
- Sponsor
- Brien Holden Vision Institute
- Enrollment
- 200
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Able to read and comprehend English and give informed consent as demonstrated by signing a record of informed consent
- •Be aged between 25 and less than 65 years old, male or female
- •Have ocular health findings considered to be normal”
Exclusion Criteria
- •Any pre\-existing ocular irritation, injury or condition (including infection or disease) of the cornea, conjunctiva or eyelids (excluding dry eye).
- •Any systemic disease that adversely affects ocular health e.g. diabetes, Graves disease, androgen deficiency and auto immune diseases such as ankylosing spondylitis, multiple sclerosis, Sjögrens syndrome, acne rosacea and systemic lupus erythematosus. Conditions such as systemic hypertension and arthritis do not automatically exclude prospective participants.
- •Concurrent punctal occlusion
- •Use of or a need for concurrent category S4 and above ocular medication at enrolment and/or during the clinical trial.
- •Use of or a need for any systemic medication or topical medications which may alter normal ocular findings / are known to affect a participant’s ocular health / physiology either in an adverse or beneficial manner at enrolment and/or during the clinical trial e.g. hormone replacement therapy or anti\-androgen therapy.
- •NB: Systemic antihistamines are allowed on an as needed basis”, provided they are not used prophylactically during the trial and at least 24 hours before the clinical trial product is used.
- •Eye surgery within 12 weeks immediately prior to enrolment for this trial.
- •Previous corneal refractive surgery.
- •Known allergy or intolerance to ingredients in any of the diagnostic products used during the clinical trial.
- •Currently enrolled in another clinical trial.
Outcomes
Primary Outcomes
Not specified
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