Efficacy of the fluoride varnish enamelast for preventing white-spot lesions and gingivitis in fixed orthodontic treatment of patients with low to moderate caries risk - a randomized controlled trial

Poliklinik für Kieferorthopädie,Universitätsklinikum Regensburg0 个研究点目标入组 101 人开始时间: 2017年6月8日最近更新: 2024年8月19日

适应症

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•Patients before starting a fixed orthodontic therapy in buccal technique (in both dental arches) with a minimum expected treatment period of 6 months,
•Bonding of brackets in the upper and lower arch on the same day (T0).
•no previous or paused fixed orthodontic therapy
•all permanent incisors, canines and premolars in both arches are present or erupted (5-5)
•All anterior teeth and premolars in both arches are intended to be fit with a bracket (20 tooth surfaces / participant).

•Patients = 18 years (adults)
•Pregnancy or lactation
•Application of a dental fluoride varnish or other caries-protective varnish preparations within the last 12 months
•Patients with a high caries risk (corresponding to 4 assessment parameters)
•Enamel alterations (fluorosis, hypocalcification, etc.)
•Fillings and restorations in buccal tooth surfaces (with bracket)
•Syndrome patients and patients with reduced oral hygiene ability or ability to perform the study properly
•systemic, endocrine or oral diseases (diabetes, periodontitis, open oral wounds / ulcers, etc.), poor general condition
•alcohol / drug abuse, smoking (tobacco), long-term medications or antibiotics / antisialoga / steroids or other medicines affecting the saliva, biofilm or the periodontal apparatus in the last 6 months
•local fluoride content in domestic drinking water > 0.2ppm F-
•Allergy / intolerance to fluorides or the preparations used
•Missing written consent
•Patients who are not prepared to comply with the protocol (no additional fluoride / PZR, dental treatment in consultation with orthodontists, oral hygiene, etc.)

发起方

Poliklinik für Kieferorthopädie,Universitätsklinikum Regensburg