A randomized, comparative study of Budesonide/formoterol versus Fluticasone/Salmeterol in COPD with asthma patients to improve oxidative stress and inflammatory mediators
Phase 2
Recruiting
- Conditions
- COPD with asthma
- Registration Number
- JPRN-UMIN000005204
- Lead Sponsor
- Jikei University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Not provided
Exclusion Criteria
1.patients with other respiratory illness(IPF, ABPA, Chug-Strass syndrome, lung cancer, tuberculosis, bronchiectasis etc) 2.patients with circulatory illness( heart failure etc) 3.past allergic history to ICS
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method improvement in the urine samples of 8-OhdG/Cr and in the blood serum of TNF-a, hs-CRP amounts.
- Secondary Outcome Measures
Name Time Method frequency of asthma attacks, ACT score, improvement in the respiratory functions(FEV1.0 etc), frequency of getting upper tract infections