To Compare the peripheral perfusion index and serum lactate levels as a marker of tissue perfusion in patients undergoing elective open heart surgery with cardiopulmonary bypass
- Conditions
- Health Condition 1: I083- Combined rheumatic disorders of mitral, aortic and tricuspid valves
- Registration Number
- CTRI/2024/01/061997
- Lead Sponsor
- Dr Prakash Chandra
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 50
All patients with American Society of Anaesthesiologists Physical Status 3 or 4 of age 20 to 60 years planned for elective open heart surgery under cardiopulmonary bypass
Patients with history of severe hepatic renal dysfunction and Chronic obstructive pulmonary disease with FEV1 less than 50 percent
Patients with cyanotic heart disease
Patients with left ventricular ejection fraction less than 40 percent
Patients undergoing combined surgical procedures CABG combined with valve surgery or aortic procedures and carotid surgery
Redo-procedures within one year of previous surgery
Patients with serum lactate more than 3 mmol per litre preoperatively
Patients with BMI of more than 32 kg per meter square
Pregnant patients
Patients with sepsis and shock states
Patients with nail pathologies
Patients in whom modified Allens test could not be performed or is negative
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare and correlate the peripheral perfusion index with serum lactate levelsTimepoint: T1 preCPB <br/ ><br>T2 cooling <br/ ><br>T3 hypothermia <br/ ><br>T4 rewarming <br/ ><br>T5 post- CPB <br/ ><br>T6 6 hours postoperatively <br/ ><br>T7 12 hours postoperatively <br/ ><br>T8 24 hours postoperatively
- Secondary Outcome Measures
Name Time Method To correlate changes in peripheral perfusion index & serum lactate values with changes in haemodynamic indicesTimepoint: T1 pre CPB <br/ ><br>T2 cooling <br/ ><br>T3 hypothermia <br/ ><br>T4 rewarming <br/ ><br>T5 post- CPB <br/ ><br>T6 6 hours postoperatively <br/ ><br>T7 12 hours postoperatively <br/ ><br>T8 24 hours postoperatively