Evaluation of the efficacy of Egg Shell derived NanoHydroxyapatite graft in Intrabony defects: A Clinical and Radiographic Study

Hydroxyapatite [HA] is apatite calcium phosphate. HA shows highest level of bioactivity and forms a quick bond with bone. The eggshell is a ubiquitous source of HA, and nanotechnology has made it possible to elicit a veritable biomaterial1.EnHA meets the required criteria and properties of an ideal graft substitute with its inherent porosity and osteotransconductivity. Lack of disease transfer risks, biocompatibility, and ease of use makes EnHA a viable source as regenerative material. EnHA is hydrophilic in nature, absorbed by body fluids and blood, so that handling becomes easy for placing it in the surgical site.The clinical studies have demonstrated the significant role of conventional graft materials in bone regeneration in periodontal intrabony defects. But to the best of our knowledge, there are limited studies on eggshell derived nanohydroxyapatite (EnHA) as a graft material in an intrabony defect. Hence the present study is planned to evaluate the effectiveness of EnHA graft in regeneration of bone in periodontal intra bony defects using a precise technology such as Cone Beam Computed Tomography [CBCT].