Study to compare improvement in skin and side effects of two oral drugs (Vitamin D and acitretin) in patients of congenital non syndromic ichthyosis

Phase 1

• Conditions: Health Condition 1: Q80- Congenital ichthyosis

• Registration Number: CTRI/2018/10/015978
• Lead Sponsor: Department of Dermatology Venereology and Leprology

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

1.Non syndromic congenital ichthyosis patients regardless of age and sex.

2.Women of child bearing potential if using adequate contraception.

3.Patients with either normal vitamin D levels or low vitamin D levels not having any clinical or radiological manifestations of rickets.

4.Patients who can give valid consent.

5.Willing for monthly follow-up visits for at least 6 months.

Exclusion Criteria

1.Ichthyosis vulgaris

2.XLRI involving less than 10% body surface area.

3.Pregnant and lactating mothers.

4.Systemic treatment within 4 weeks prior to the start of treatment phase.

5.Patients with hypercalcemia or high vitamin D, and significant renal or hepatic disease.

6.Patients with severe hypovitaminosis D affecting bone health as assessed clinically and radiologically.

7.Inability to come for monthly follow up visits for 6 months

8.Those who cannot provide consent for the study

Study & Design

• Study Type: Interventional
• Study Design: Not specified