Pain Relief of Metoprolol Versus Metoprolol Plus Morphine in Acute Chest Pain

Phase 4

Completed

• Conditions: Acute Coronary Syndromes
• Interventions: Drug: Metoprolol; Drug: metoprolol plus morphine

• Registration Number: NCT00718406
• Lead Sponsor: Sahlgrenska University Hospital, Sweden

Brief Summary

The primary aim was to evaluate the relief of chest pain during the first 30 minutes among patients who received metoprolol alone as compared with metoprolol plus morphine

Detailed Description

Not available

Study Timeline

• Status Verified: 2002-08
• Study First Submitted: 2008-07-16
• Study First Submitted QC: 2008-07-16
• Last Update Submitted: 2008-07-16
• Study First Posted: 2008-07-18
• Last Update Posted: 2008-07-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• Acute chest pain
• ECG-signs indicating myocardial ischemia

Exclusion Criteria

• Heart rate < 60 beats/min
• Systolic blood pressure < 110 mmHg
• High degree AV-block
• Signs of obstructive pulmonary disease
• Signs of pulmonary oedema
• Unwillingness
• Participation in other studies
• Long delay between arrival of ambulance and randomisation

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
A	Metoprolol	A=metoprolol
B	metoprolol plus morphine	B=metoprolol plus morphine

Trial Locations

Locations (1)

Medical Institution, Dept of Molecular and Clinical Medicine, Sahlgrenska University Hospital; 🇸🇪 Göteborg, Sweden