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Clinical Trials/NCT00692302
NCT00692302
Completed
Phase 1

Family Based Intervention for Adolescent Suicide Attempters

University of California, Los Angeles1 site in 1 country72 target enrollmentMarch 2006
ConditionsSuicide

Overview

Phase
Phase 1
Intervention
Not specified
Conditions
Suicide
Sponsor
University of California, Los Angeles
Enrollment
72
Locations
1
Primary Endpoint
Suicide Attempt
Status
Completed
Last Updated
last year

Overview

Brief Summary

This study will evaluate the effectiveness of an individually tailored suicide prevention treatment program called SAFETY in reducing suicide and suicide attempts in adolescents.

Detailed Description

Suicide is consistently a leading cause of death among adolescents in the United States, making suicide prevention a serious public health concern. The risk factors for suicide vary but are often related to depression and other mental disorders, substance abuse, a major stressful event, and family history of suicide. Despite the morbidity and mortality associated with suicide attempts in adolescents, there is a lack of empirically supported treatment strategies and consensus regarding the best practices for suicide prevention. The SAFETY intervention is an individually tailored treatment strategy that integrates family- and community-based interventions and cognitive behavioral therapy and links youth to needed services and resources. SAFETY may be an effective means of reducing suicide attempts and improving mental health in at-risk adolescents. This study will evaluate the effectiveness of SAFETY in reducing suicide and suicide attempts in adolescents. This study will be divided into two phases. Participants in Phase I will all receive 12 weeks of the family-based cognitive behavioral therapy intervention SAFETY. Phase I will be used to develop the intervention manual, protocols, and adherence measures for SAFETY in Phase II. Phase I participants will undergo assessments at baseline and Week 12. Assessments will last 90 minutes and will include a series of interviews and questionnaires concerning family, general health, and mental health-related issues. Participants in Phase II will be assigned randomly to receive 12 weeks of SAFETY or enhanced usual care. The frequency of sessions, which will involve both youth and parent participants, will vary on the basis of the individual needs of participants. SAFETY sessions will be individually tailored for each participant's specific needs and will include the following elements: (1) family- and community-based interventions aimed at mobilizing family and community networks that support youth safety, adaptive behavior, and reasons for living; (2) cognitive behavioral treatment modules that focus on decreasing suicidality and preventing repeat suicide attempts; and (3) an individualized care linkage strategy that links youth to needed services and resources. At baseline, Week 12, and Month 6, all youth and parent participants will undergo the same assessments that were performed during Phase I.

Registry
clinicaltrials.gov
Start Date
March 2006
End Date
October 18, 2019
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Joan Asarnow

Professor of Psychiatry & Biobehavioral Sciences

University of California, Los Angeles

Eligibility Criteria

Inclusion Criteria

  • Suicide attempt or repetitive self-harm in the 3 months before study entry

Exclusion Criteria

  • Psychosis
  • Substance dependency
  • Immediate risk of out-of-home placement
  • Symptoms/conditions that would interfere with assessment and/or intervention protocols

Outcomes

Primary Outcomes

Suicide Attempt

Time Frame: 3-months

Derived from adapted C-SSRS that incorporates questions from the Suicide History Interview

Suicide-related hospitalizations

Time Frame: Measured at month 3

SACA, adapted

Study Sites (1)

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