Paroxysmal Positional Vertigo & Repositioning Maneuvers

Not Applicable

Completed

• Conditions: Benign Paroxysmal Positional Vertigo
• Interventions: Other: Modified eply & Semont maneuver; Other: betahistine & Modified eply & Semont maneuver

• Registration Number: NCT05309538
• Lead Sponsor: Neuro Counsel Hospital, Pakistan

Brief Summary

: Benign Paroxysmal Positional Vertigo is a condition related to vestibular system accompanied by dizziness, tinnitus and balance problems leading to increased fall risk and potential disability. Various treatment options are available including pharmacotherapy and vestibular rehabilitation with varied results

Detailed Description

Objective: The objective of this study was to compare the efficacy of Modified Epley \& Semont's maneuver with and without Betahistine for BPPV Material \& Methods: The study was a single blind randomized control trail. Total number of patients were 97 as calculated by Epitool calculator. Duration of the study was of one year from 2 January 2021 to 1st January 2022. Out of a total 97 patients, 90 met the inclusion criteria. These participants were randomized by lottery method into two equal groups. Group A (control group) was receiving both maneuvers only while group B (experimental group) included participants receiving betahistine along with both maneuvers. The impact of dizziness and quality of life was measured through EQ-5D-5L questionnaire and dizziness handicap inventory (DHI) in order to analyze the effectiveness of treatments. Pre and Post treatment results were compared within group by Wilcoxon rank test and for between groups, Mann Whitney U test was performed

Study Timeline

• Study Start: 2021-01-02
• Primary Completion: 2022-01-01
• Study Completion: 2022-01-01
• Study First Submitted: 2022-03-24
• Status Verified: 2022-04
• Study First Submitted QC: 2022-04-01
• Last Update Submitted: 2022-04-01
• Study First Posted: 2022-04-04
• Last Update Posted: 2022-04-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

• age between 18-60
• positive modified Dix Hil pike test
• repetitive vertigo spells affecting activities of daily livings (ADLs)

Exclusion Criteria

• any cervical spine problem
• vertigo due to central disease
• tumors
• systemic disease
• cardiac disease
• Parkinson disease
• bed bound patients

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Group A	Modified eply & Semont maneuver	Control group
group B	betahistine & Modified eply & Semont maneuver	experimental group

Primary Outcome Measures

Name	Time	Method
EQ-5D-5L	1 month	quality of life
DHI	1 month	dizziness handicap inventery

Trial Locations

Locations (1)

the Neurocouncil Clinic; 🇵🇰 Islamabad, Fedral, Pakistan