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Balance Control in Children With Cerebral Palsy

Not Applicable
Conditions
Cerebral Palsy
Interventions
Procedure: Sensory Integration Testing
Procedure: SR stimulation & Sensory integration testing
Registration Number
NCT02456376
Lead Sponsor
Temple University
Brief Summary

The purpose of this study is to investigate how sensory information processing affects balance ability in children with cerebral palsy (CP). An additional goal is to determine if a subsensory electrical stimulation called Stochastic Resonance (SR) Stimulation, can improve balance in children with CP. Children with CP and children with typical development will participate and complete a series of clinical and balance assessments. They will also be tested in a sensor fusion paradigm to investigate potential deficits in the dynamic integration of visual, vestibular and proprioceptive information during upright stance. SR stimulation will then be used to potentially improve these deficits and subsequently their balance ability.

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
20
Inclusion Criteria
  • Diagnosis of spastic diplegia CP (GMFCS I- III)*
  • Ability to stand independently for approximately 2 min
Exclusion Criteria
  • Lower extremity surgery or fractures in the year prior testing

  • Joint instability or dislocation in the lower extremities

  • Botulinum toxin injections in the lower extremities within the past 6 months*

  • Marked visual or hearing deficits

  • Uncontrolled seizure disorder

  • Implanted medical device that may be contraindicated with application of SR stimulation

    • Asterisk indicates the eligibility criteria that should be met only by children with CP

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Children with Cerebral palsySensory Integration Testing1. Sensory integration testing 2. SR stimulation and Sensory integration testing
Children with Typical DevelopmentSensory Integration Testing1. Sensory integration testing 2. SR stimulation and Sensory integration testing
Children with Cerebral palsySR stimulation & Sensory integration testing1. Sensory integration testing 2. SR stimulation and Sensory integration testing
Children with Typical DevelopmentSR stimulation & Sensory integration testing1. Sensory integration testing 2. SR stimulation and Sensory integration testing
Primary Outcome Measures
NameTimeMethod
Gain response1 day

For both the sensory reweighting testing, the visual signal will be displayed as a visual flow with translation in anterior-posterior (AP) direction (i.e., sagittal plane) and presented at different amplitudes (0.25 and 0.5 cm) at 0.2 Hz to measure: the change in gain (weighting) to vision (intramodal effect); and a change in gain to vibration and galvanic stimulation (intermodal effects). Gain for each modality relative to both the leg segment AP translation and trunk segment AP translation will be measured.

Secondary Outcome Measures
NameTimeMethod
Gain response1 day

For the sensory reweighting with the addition of SR stimulation testing, the visual signal will be displayed as a visual flow with translation in anterior-posterior (AP) direction (i.e., sagittal plane) and presented at different amplitudes (0.25 and 0.5 cm) at 0.2 Hz to measure: the change in gain (weighting) to vision (intramodal effect); and a change in gain to vibration and galvanic stimulation (intermodal effects). Gain for each modality relative to both the leg segment AP translation and trunk segment AP translation will be measured.

Trial Locations

Locations (2)

Temple University

🇺🇸

Philadelphia, Pennsylvania, United States

Shriners Hospital for Children

🇺🇸

Philadelphia, Pennsylvania, United States

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