Study the association between motherâ??s first trimester characteristics, ultrasound findings ,blood investigations with pregnancy complications
- Conditions
- Health Condition 1: O098- Supervision of other high risk pregnancies
- Registration Number
- CTRI/2021/03/032233
- Lead Sponsor
- Kasturba medical college Manipal
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
For controls- All low risk pregnancies who deliver in Kasturba medical college, manipal in the study period and who have information available regarding their maternal baseline characteristics, ultrasound findings and complete laboratory report.
For cases- All the complicated cases who will be attended in kasturba medical college, manipal in the study period and have information available regarding their maternal baseline characteristics, ultrasound findings and complete laboratory report.
All the cases who will be attended in kasturba medical college, manipal in the study period and do not have information available regarding their maternal baseline characteristics, ultrasound findings and complete laboratory report.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To study pregnancy complications ( second trimester abortions/congenital malformatioms & chromosomal abnormalities/ preeclampsia/gestational diabetes mellitus/ intra-uterine growth restriction/ spontaneous preterm delivery/stillbirths ) and their association with first trimester maternal characteristics( age/height/weight/BMI/previous significant obstetric history),sonological features( croen rumo length/uterine artery doppler)and serum analytes( HbA1c/ PAPP-A/ Beta-hcg/ placental growth factor)Timepoint: Maternal characteristics will be noted in the booking visit <br/ ><br>Serum analyte values will be noted after the first basic antenatal blood tests <br/ ><br>Sonological features will be noted between 11-13 weeks of pregnancy during NT scan <br/ ><br>Pregnancy complications will be noted during the course of pregnancy
- Secondary Outcome Measures
Name Time Method To study fetal outcomesand their association with first trimester maternal characteristics(age/height/weight/BMI/previous significant obstetric history),sonological features( croen rumo length/uterine artery doppler)and serum analytes( HbA1c/ PAPP-A/ Beta-hcg/ placental growth factor)Timepoint: Delivery details will be noted <br/ ><br>fetal outcome in terms of term/preterm birth, birth weight, APGAR score, NICU admission will be noted