The effect, safety and money saving difference between two blood pressure medicines olmesartan and telmisartan.
Phase 4
- Conditions
- Health Condition 1: I10- Essential (primary) hypertension
- Registration Number
- CTRI/2023/10/058698
- Lead Sponsor
- ESIC Medical College and Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Adult patients aged 18 years or older
2.Patients who are newly diagnosed with hypertension.
3.Patients of either gender.
Exclusion Criteria
1.Patients receiving any other antihypertensive medication, corticosteroids and immunosuppressive agents
2.Patient with history of renal disease.
3.Pregnant and lactating women
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.To compare the cost-effectiveness of olmesartan & telmisartan on reducing blood pressure. <br/ ><br>2.To compare the effect of olmesartan & telmisartan on blood pressure in newly diagnosed hypertensive patients. <br/ ><br>3.To compare the tolerability of olmesartan and telmisartanTimepoint: 1.Blood pressure will be assessed at baseline,2nd week,4th week,8th week,12th week. <br/ ><br>2.tolerability is checked by adverse effects profile at baseline and at 12th week <br/ ><br>3.cost-effectiveness assessed by ICER ratio at 12th week. <br/ ><br>
- Secondary Outcome Measures
Name Time Method To evaluate & compare the effect of olmesartan & telmisartan on fasting lipid profile, fasting blood sugar & renal function(serum creatinine). <br/ ><br>Timepoint: The percentage reduction of fasting blood sugar, fasting lipid profile & renal function(serum creatinine) by 10% of the base line value. <br/ ><br>