ACTRN12614001219673
Completed
未知
Multiparametric MRI as a Predictor of Tumour Response in Patients with Anal Canal Cancer Managed with Chemoradiotherapy
Dr Michael Jones0 sites20 target enrollmentNovember 19, 2014
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Anal Cancer
- Sponsor
- Dr Michael Jones
- Enrollment
- 20
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\.Patient capable of providing informed consent
- •2\.Patient deemed suitable for protocol treatment as
- •assessed by Radiation and Medical Oncologists
- •3\.Histological diagnosis of invasive primary squamous
- •cell carcinoma of the anal canal
- •4\.TNM Stage: T2\-4, N0\-3 based on the
- •following diagnostic workup
- •a.History \& physical examination
- •b.Digital Rectal Exam (DRE) stating primary size and
- •distance from anal verge
Exclusion Criteria
- •1\.ECOG performance status \>2
- •2\.Significant comorbidities that would interfere with
- •the completion of treatment
- •3\.Renal insufficiency (Creatinine \> 150\)
- •4\.Prior radiotherapy to the pelvis that would overlap in
- •the treatment fields
- •5\.Prior surgery for cancer of the anus that removed all
- •macroscopic cancer
- •6\.Prior systemic chemotherapy for anal cancer
- •7\.Evidence of distant metastases (M1\) if this precludes
Outcomes
Primary Outcomes
Not specified
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