Acetazolamide as a treatment after hemorrhagic stroke
Completed
- Conditions
- aneurysmal subarachnoid hemorrhage
- Registration Number
- NL-OMON23709
- Lead Sponsor
- niversity Medical Center Utrecht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
≥18 years old
Aneurysm confirmed by the presence of subarachnoid blood by computed tomography (CT) or lumbar puncture and by visualization of the aneurysm on either CT angiography, MR angiography or digital subtraction angiography
Exclusion Criteria
Intensive care (IC) required for >72 hours after ictus (i.e., during inclusion window)
Perimesencephalic bleeding
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Cerebral perfusion (arterial spin labeling (ASL) MRI) on day 7±2 after ictus.
- Secondary Outcome Measures
Name Time Method Cerebral perfusion (arterial spin labeling (ASL) MRI) on day 12±2 after ictus.<br /><br>Serious adverse events (SAEs) and serious unexpected serious adverse reactions (SUSARs) until 10 weeks after ictus.<br /><br>The occurrence of DCI. DCI will be defined as either clinical deterioration or cerebral infarction due to delayed cerebral ischemia”.