Comparative Analgesic Effect Between Continuous Wound Infusion and Transverse Abdominal Plan Block for Abdominoplasty Surgery
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Surgery of Abdominoplasty With Flank Liposuction
- Sponsor
- University of Liege
- Enrollment
- 50
- Locations
- 1
- Primary Endpoint
- Pain score expressed on a visual analogue scale
- Last Updated
- 5 years ago
Overview
Brief Summary
The purpose of this randomized controlled study is to compare the postoperative analgesic effect of a continuous wound infusion of local anesthetics and a sole transverse abdominal plan (TAP) regional block in the surgery of Abdominoplasty Combined With Flank Liposuction. Local anesthetics products used are ropivacaine combined with clonidine. Similar amount of local anesthetics and clonidine are used.
Detailed Description
In a first group, patients receive, after induction of anaesthesia and before surgery, a TAP block (transverse abdominal plan block) with 3mg/kg Ropivacaine 0.5% (maximum 200 mg) and 150 microg Clonidine. In a second group, before skin closure, a multiholes catheter was inserted beyond the skin. 20 mg Ropivacaine 0.2% added with 150 microg Clonidine was injected as bolus dose through this catheter followed by a continuous infusion of Ropivacaine 0.2% 10ml per hour during the following 9 hours (total dose of 200 mgr).
Investigators
J P Lecoq
MD
University of Liege
Eligibility Criteria
Inclusion Criteria
- •Patients scheduled for abdominoplasty combined with flank liposuction
Exclusion Criteria
- •Allergy to local anesthetics or clonidine
- •Coagulation disorders
- •History of chronic pain
- •Alcohol or drugs dependance
- •Refusal of the patients
Outcomes
Primary Outcomes
Pain score expressed on a visual analogue scale
Time Frame: at 0,2,4,6, 8 hours, and day 1 and day 2 postoperatively
Secondary Outcomes
- Piritramide consumption on Patient Controlled Analgesia (PCA) device(at 0,2,4,6, 8 hours, and day 1 and day 2 postoperatively)
- Scale of nausea(at 0,2,4,6, 8 hours, and day 1 and day 2 postoperatively)
- Scale of sedation(at 0,2,4,6, 8 hours, and day 1 and day 2 postoperatively)
- Scale of patient's satisfaction(at day 2 postoperatively)
- Number of patients with adverse events(daily during 48 hours postoperatively)