Anti-infective effect of non-surgical treatment with and without photodynamic therapy on peri-implantitis: a pilot multicenter prospective randomized controlled clinical trial

Klinik für Mund-, Kiefer- und Gesichtschirurgie im UKSH, Campus Kiel0 个研究点目标入组 3 人开始时间: 2016年12月22日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•- Subjects with at least one implant with peri-implantitis. The peri-implantitis is defined as: PPD of 4-6mm combined with BOP+, and bone loss of 2-4mm on peri-apical radiographs (taken by paralleling technique with splints for reproducible X-rays) compared to the time point of restoration placement.
•- Availability for the 12 month duration of the study
•- Signed Informed Consent Form.

•- Subject with severe systemic diseases. (e.g. uncontrolled hypertension, uncontrolled diabetes, severe coagulation disorder, acute hepatitis, acute nephritis and myocardial infarction history less than 6 months).
•- Pregnant or lactating females
•- Patients have history of periodontitis
•- Patients have history of receiving bisphosphonate therapy
•- Peri-implant mucositis defined as the absence of radiographic marginal bone loss between restoration placement and pre-screening review
•- Subjects treated for >2 weeks with any medication known to affect soft tissue condition (e.g. phenytoin, calcium antagonists, cyclosporin, Coumadin and non-steroidal anti-inflammatory drugs) within 1 month of the prescreening examination
•- Allergy to dye phenothiazine chlorid (Toloniumchlorid or Toluidinblue) or mouth rinse with chlorhexidine
•- Unwilling to participate in the study.

发起方

Klinik für Mund-, Kiefer- und Gesichtschirurgie im UKSH, Campus Kiel